Epidemiology and Diagnosis of Acute Nonvariceal Upper Gastrointestinal Bleeding

被引:96
作者
Rotondano, Gianluca [1 ]
机构
[1] Hosp Maresca, Div Gastroenterol & Digest Endoscopy, ASLNA3sud, I-80059 Torre Del Greco, Italy
关键词
Nonvariceal bleeding; Epidemiology; Diagnosis; Risk factors; Peptic ulcer; Endoscopy; Timing; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; LOW-DOSE ASPIRIN; HOSPITAL ADMISSION; PREDICTING MORTALITY; EARLY ENDOSCOPY; VISIBLE VESSEL; UNITED-STATES; RISK-FACTORS; TIME TRENDS; MANAGEMENT;
D O I
10.1016/j.gtc.2014.08.001
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Acute upper gastrointestinal bleeding (UGIB) is a common gastroentero-logical emergency. A vast majority of these bleeds have nonvariceal causes, in particular gastroduodenal peptic ulcers. Nonsteroidal anti-inflammatory drugs, low-dose aspirin use, and Helicobacter pylori infection are the main risk factors for UGIB. Current epidemiologic data suggest that patients most affected are older with medical comorbidit. Widespread use of potentially gastroerosive medications underscores the importance of adopting gastroprotective pharamacologic strategies. Endoscopy is the mainstay for diagnosis and treatment of acute UGIB. It should be performed within 24 hours of presentation by skilled operators in adequately equipped settings, using a multidisciplinary team approach.
引用
收藏
页码:643 / +
页数:22
相关论文
共 97 条
[61]   Predicting mortality in patients with in-hospital nonvariceal upper GI bleeding: a prospective, multicenter database study [J].
Marmo, Riccardo ;
Koch, Maurizio ;
Cipolletta, Livio ;
Bianco, Maria Antonia ;
Grossi, Enzo ;
Rotondano, Gianluca .
GASTROINTESTINAL ENDOSCOPY, 2014, 79 (05) :741-+
[62]   Mortality from nonulcer bleeding is similar to that of ulcer bleeding in high-risk patients with nonvariceal hemorrhage: a prospective database study in Italy [J].
Marmo, Riccardo ;
Del Piano, Mario ;
Rotondano, Gianluca ;
Koch, Maurizio ;
Bianco, Maria Antonia ;
Zambelli, Alessandro ;
Di Matteo, Giovanni ;
Grossi, Enzo ;
Cipolletta, Livio .
GASTROINTESTINAL ENDOSCOPY, 2012, 75 (02) :263-272
[63]   Predicting Mortality in Non-Variceal Upper Gastrointestinal Bleeders: Validation of the Italian PNED Score and Prospective Comparison With the Rockall Score [J].
Marmo, Riccardo ;
Koch, Maurizio ;
Cipolletta, Livio ;
Capurso, Lucio ;
Grossi, Enzo ;
Cestari, Renzo ;
Bianco, Maria A. ;
Pandolfo, Nicola ;
Dezi, Angelo ;
Casetti, Tino ;
Lorenzini, Ivano ;
Germani, Ugo ;
Imperiali, Giorgio ;
Stroppa, Italo ;
Barberani, Fausto ;
Boschetto, Sandro ;
Gigliozzi, Alessandro ;
Gatto, Giovanni ;
Peri, Vittorio ;
Buzzi, Andrea ;
Della Casa, Domenico ;
Di Cicco, Marino ;
Proietti, Massimo ;
Aragona, Giovanni ;
Giangregorio, Francesco ;
Allegretta, Luciano ;
Tronci, Salvatore ;
Michetti, Paolo ;
Romagnoli, Paola ;
Piubello, Walter ;
Ferri, Barbara ;
Fornari, Fabio ;
Del Piano, Mario ;
Pagliarulo, Michela ;
Di Mitri, Roberto ;
Trallori, Giacomo ;
Bagnoli, Sirio ;
Frosini, Giorgio ;
Macchiarelli, Raffaele ;
Sorrentini, Italo ;
Pietrini, Lorena ;
De Stefano, Salvatore ;
Ceglia, Tommaso ;
Chiozzini, Giorgio ;
Salvagnini, Mario ;
Di Muzio, Daniela ;
Rotondano, Gianluca .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (06) :1284-1291
[64]   Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials [J].
McQuaid, Kenneth R. ;
Laine, Loren .
AMERICAN JOURNAL OF MEDICINE, 2006, 119 (08) :624-638
[65]   Non-Variceal Upper GI Bleeding in Patients Already Hospitalized for Another Condition [J].
Mueller, Tanja ;
Barkun, Alan N. ;
Martel, Myriam .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2009, 104 (02) :330-339
[66]   Epidemiological and prognostic factors involved in upper gastrointestinal bleeding: results of a French prospective multicenter study [J].
Nahon, S. ;
Hagege, H. ;
Latrive, J. P. ;
Rosa, I. ;
Nalet, B. ;
Bour, B. ;
Faroux, R. ;
Gower, P. ;
Arpurt, J. P. ;
Denis, J. ;
Henrion, J. ;
Remy, A. J. ;
Pariente, A. .
ENDOSCOPY, 2012, 44 (11) :998-1006
[67]   Esomeprazole Compared With Famotidine in the Prevention of Upper Gastrointestinal Bleeding in Patients With Acute Coronary Syndrome or Myocardial Infarction [J].
Ng, Fook-Hong ;
Tunggal, P. ;
Chu, Wai-Ming ;
Lam, Kwok-Fai ;
Li, Andrew ;
Chan, Kit ;
Lau, Yuk-Kong ;
Kng, Carolyn ;
Keung, K. K. ;
Kwan, Ambrose ;
Wong, Benjamin C. Y. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2012, 107 (03) :389-396
[68]   End-stage renal disease is associated with worse outcomes in hospitalized patients with peptic ulcer bleeding [J].
Parasa, Sravanthi ;
Navaneethan, Udayakumar ;
Sridhar, Arun Raghav Mahankali ;
Venkatesh, Preethi G. K. ;
Olden, Kevin .
GASTROINTESTINAL ENDOSCOPY, 2013, 77 (04) :609-616
[69]   Burden of Gastrointestinal Disease in the United States: 2012 Update [J].
Peery, Anne F. ;
Dellon, Evan S. ;
Lund, Jennifer ;
Crockett, Seth D. ;
McGowan, Christopher E. ;
Bulsiewicz, William J. ;
Gangarosa, Lisa M. ;
Thiny, Michelle T. ;
Stizenberg, Karyn ;
Morgan, Douglas R. ;
Ringel, Yehuda ;
Kim, Hannah P. ;
Dibonaventura, Marco Dacosta ;
Carroll, Charlotte F. ;
Allen, Jeffery K. ;
Cook, Suzanne F. ;
Sandler, Robert S. ;
Kappelman, Michael D. ;
Shaheen, Nicholas J. .
GASTROENTEROLOGY, 2012, 143 (05) :1179-+
[70]   Outcome of peptic ulcer bleeding, nonsteroidal anti-inflammatory drug use, and Helicobacter pylori infection [J].
Ramsoekh, D ;
van Leerdam, ME ;
Rauws, EAJ ;
Tytgat, GNJ .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2005, 3 (09) :859-864