One-Pot Preparation of (E)-α,β-Unsaturated Aldehydes by a Julia-Kocienski Reaction of 2,2-Dimethoxyethyl PT Sulfone Followed by Acid Hydrolysis

被引：4
作者：
Ando, Kaori [1 ]
Watanabe, Haruka [1 ]
Zhu, Xiaoxian [1 ]
机构：
[1] Gifu Univ, Fac Engn, Dept Chem & Biomol Sci, Gifu 5011193, Japan
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 86卷 / 09期
关键词：
ALPHA; BETA-UNSATURATED ALDEHYDES; STEREOSELECTIVE-SYNTHESIS; 2-CARBON HOMOLOGATION; KETONES; DERIVATIVES; ALCOHOLS;
D O I：
10.1021/acs.joc.1c00479
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
(E)-alpha,beta-Unsaturated aldehydes were synthesized by the Julia-Kocienski reaction of 2,2-dimethoxyethyl 1-phenyl-1H-tetrazol-5-yl (PT) sulfone 3 with various aldehydes, followed by acid hydrolysis. The reaction could be carried out in one pot, and various (E)-alpha,beta-unsaturated aldehydes were obtained in a short time and with high yields.
引用
收藏
页码：6969 / 6973
页数：5
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