Whole-Body Vibration Effects on Bone Mineral Density in Women With or Without Resistance Training

HUMPHRIES B, FENNING A, DUGAN E, GUINANE J, MACRAE K. Whole-body vibration effects oil bone mineral density ill women With or without resistance training. Aviat Space Environ Med 2009; 80:1025-31. Introduction: Whole-body vibration exposure may translate into improved bone mass in young adult women. The primary focus of this study was to examine the effects of graded whole-body vibration or vibration exposure plus resistance training on bone mineral density (BMD), hematological measures for bone remodeling, and exercise metabolism in young women. Methods: There were 51 healthy active women [mean (SD) age, 21.02 (3.39) yr; height, 165.66 (6.73) cm; body mass 66.54 (13.39) kg] who participated in the intervention. Subjects were randomly assigned to whole-body vibration (WBV), whole-body vibration plus resistance training (WBV+RT), or control (CONT) groups for 16 wk. Results: A repeated-measure ANOVA found no significant (P < 0.05) group differences in BMD at the completion of 16 wk. A significant within group) change was apparent for the WBV (2.7% femoral neck) and WBV+RT (femoral neck 1.9%; vertebra 0.98%). WBV and WBV+RT experienced a significant (P < 0.05) 60%, and 58% increase in adiponectin, 48% and 30% in transforming growth factor-beta 1, and 17% and 34% in nitric oxide with an accompanying 50% and 36% decrease in osteopontin, 19% and 34% in interleukin-1 beta, and 38%, and 39%, in tumor necrosis factor-alpha. Conclusions: The results indicate graded wholebody vibration exposure may be effective in improving BMD by increasing bone deposition while also decreasing bone resorption. Whole-body vibration may also provide an efficient stratagem for young women to achieve peak bone mass and hell) stave off osteoporosis later in life and provide a novel form of physical training.