Comparative biology of human and canine osteosarcoma

被引:0
作者
Mueller, F.
Fuchs, B.
Kaser-Hotz, B.
机构
[1] Univ Zurich, Vetsuisse Fac, Sect Diagnost Imaging & Radiat Oncol, CH-8057 Zurich, Switzerland
[2] Univ Zurich, Balgrist Univ Hosp, Dept Orthopaed, Zurich, Switzerland
关键词
osteosarcoma; comparative biology; dog model; review; TUMOR-SUPPRESSOR GENE; GROWTH-FACTOR-I; ALKALINE-PHOSPHATASE ACTIVITY; LIPOSOMAL MURAMYL TRIPEPTIDE; OSTEO-SARCOMA; APPENDICULAR OSTEOSARCOMA; PROGNOSTIC FACTORS; CELL-LINES; CYCLOOXYGENASE-2; EXPRESSION; ADJUVANT CHEMOTHERAPY;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Dogs with osteosarcoma provide an important model for the same disease in humans. In this report, the comparative nature of human and canine osteosarcoma including incidence and risk factors, clinical presentation and diagnosis, genetic abnormalities, biologic behaviour and prognostic factors, as well as treatment options are reviewed.
引用
收藏
页码:155 / 164
页数:10
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