Ginkgo biloba and Ginkgotoxin

被引：86

作者：

Leistner, Eckhard ^{[1
]}

Drewke, Christel ^{[1
]}

机构：

[1] Univ Bonn, Inst Pharmazeut Biol, D-53115 Bonn, Germany

来源：

JOURNAL OF NATURAL PRODUCTS | 2010年 / 73卷 / 01期

关键词：

GAMMA-AMINOBUTYRIC-ACID; HERB-DRUG INTERACTIONS; HUMAN PYRIDOXAL KINASE; VITAMIN-B6; BIOSYNTHESIS; GLUTAMATE-DECARBOXYLASE; MEDICINAL-PLANTS; MOUSE-BRAIN; EGB; 761; 4-O-METHYLPYRIDOXINE; PHOSPHATE;

D O I：

10.1021/np9005019

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Products prepared from Ginkgo biloba arc top-selling phytopharmaceuticals especially in Europe and major botanical dietary supplements in the United States. In European medicine, G. biloba medications arc used to improve memory, to treat neuronal disorders such its tinnitus or intermittent claudication, and to improve brain metabolism and peripheral blood flow. The whole array of indications is reflected by a number of defined natural product constituents in G. biloba. The most well-known ones are flavonoids and terpene lactones, but they also include allergenic and toxic compounds such as ginkgotoxin (1). Consequently, there are reports attributing beneficial as well as adverse effects to G. biloba products. The present paper Summarizes recent experiences with G. biloba and its derived products and explains why their restricted use is recommended.

引用

页码：86 / 92

页数：7

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