Mild Cognitive Impairment

被引：314

作者：

Sanford, Angela M. ^{[1
]}

机构：

[1] St Louis Univ, Sch Med, Dept Internal Med Geriatr, 1402 South Grand Blvd,Suite M238, St Louis, MO 63104 USA

来源：

CLINICS IN GERIATRIC MEDICINE | 2017年 / 33卷 / 03期

关键词：

Mild cognitive ltpairment; MCI; Early dernentia; Cognitive decline; Memory impairtilent; ALZHEIMERS-DISEASE; OLDER-ADULTS; NEUROCOGNITIVE DISORDER; MEDITERRANEAN DIET; PHYSICAL-ACTIVITY; MEMORY DECLINE; CSF BIOMARKERS; FOLLOW-UP; DEMENTIA; RISK;

D O I：

10.1016/j.cger.2017.02.005

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Mild cognitive impairment (MCI) occurs along a continuum from normal cognition to dementia. A roadblock to earlier diagnosis and potential treatment is the lack of consistency with screening for MCI. Universal screening would be ideal, but is limited. Once a diagnosis of MCI is made, it is important for the clinician to evaluate for reversible causes. At present time, there are no pharmacologic treatments proven to slow or cure progression of MCI to dementia; nonetheless, there is evidence that lifestyle modifications including diet, exercise, and cognitive stimulation may be effective.

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页码：325 / +

页数：15

相关论文

共 68 条

[1] Cognitive stimulation for dementia: A systematic review of the evidence of effectiveness from randomised controlled trials [J].

Aguirre, Elisa ;

Woods, Robert T. ;

Spector, Aimee ;

Orrell, Martin .

AGEING RESEARCH REVIEWS, 2013, 12 (01) :253-262

[2]

[Anonymous], EUR J NUTR

[3] Risk profiles for mild cognitive impairment and progression to dementia are gender specific [J].

Artero, S. ;

Ancelin, M-L ;

Portet, F. ;

Dupuy, A. ;

Berr, C. ;

Dartigues, J-F ;

Tzourio, C. ;

Rouaud, O. ;

Poncet, M. ;

Pasquier, F. ;

Auriacombe, S. ;

Touchon, J. ;

Ritchie, K. .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2008, 79 (09) :979-984

[4] Cognitive Status According to Homocysteine and B-Group Vitamins in Elderly Adults [J].

Bonetti, Francesco ;

Brombo, Gloria ;

Magon, Stefania ;

Zuliani, Giovanni .

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2015, 63 (06) :1158-1163

[5] Missed and Delayed Diagnosis of Dementia in Primary Care Prevalence and Contributing Factors [J].

Bradford, Andrea ;

Kunik, Mark E. ;

Schulz, Paul ;

Williams, Susan P. ;

Singh, Hardeep .

ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 2009, 23 (04) :306-314

[6]

Campbell N, 2009, CLIN INTERV AGING, V4, P225

[7]

Carter MJ, 2014, THER RECREAT J, V48, P275

[8] Longitudinal Modeling of Age-Related Memory Decline and the APOE ε4 Effect [J].

Caselli, Richard J. ;

Dueck, Amylou C. ;

Osborne, David ;

Sabbagh, Marwan N. ;

Connor, Donald J. ;

Ahern, Geoffrey L. ;

Baxter, Leslie C. ;

Rapcsak, Steven Z. ;

Shi, Jiong ;

Woodruff, Bryan K. ;

Locke, Dona E. C. ;

Snyder, Charlene Hoffman ;

Alexander, Gene E. ;

Rademakers, Rosa ;

Reiman, Eric M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (03) :255-263

[9] Persistent but not Paroxysmal Atrial Fibrillation Is Independently Associated With Lower Cognitive Function ARIC Study [J].

Chen, Lin Y. ;

Agarwal, Sunil K. ;

Norby, Faye L. ;

Gottesman, Rebecca F. ;

Loehr, Laura R. ;

Soliman, Elsayed Z. ;

Mosley, Thomas H. ;

Folsom, Aaron R. ;

Coresh, Josef ;

Alonso, Alvaro .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 67 (11) :1379-1380

[10] B vitamin supplementation improves cognitive function in the middle aged and elderly with hyperhomocysteinemia [J].

Cheng, Daomei ;

Kong, Haiyan ;

Pang, Wei ;

Yang, Hongpeng ;

Lu, Hao ;

Huang, Chengyu ;

Jiang, Yugang .

NUTRITIONAL NEUROSCIENCE, 2016, 19 (10) :461-466

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