Functional patchworking at the plasma membrane

被引：2
作者：
Leon, Sebastien [1 ]
Teis, David [2 ]
机构：
[1] Univ Paris Diderot, Inst Jacques Monod, Sorbonne Paris Cite, CNRS,UMR 7592, Paris, France
[2] Med Univ Innsbruck Austria, Bioctr, Div Cell Biol, Innsbruck, Austria
来源：
EMBO JOURNAL | 2018年 / 37卷 / 16期
关键词：
ENDOCYTOSIS; TURNOVER;
D O I：
10.15252/embj.2018100144
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Lipids and proteins are not evenly distributed within the plasma membrane (PM), but instead segregate laterally into many specialized microdomains whose functional relevance is not clear. In this issue, Busto et al (2018) demonstrate that substrate flux through a nutrient transporter drives the lateral relocation of the transporter between specific microdomains at the yeast PM, suggesting that regulating the lateral plasma membrane compartmentalization for individual proteins could be a general process for cellular response to environmental conditions.
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页数：3
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