Rakicidin C, a new cyclic depsipeptide from Streptomyces sp.

被引:3
作者
Hu, JF
Wunderlich, D
Sattler, I
Feng, XZ
Grabley, S
Thiericke, R
机构
[1] Hans Knoll Inst Nat Prod Res, D-07745 Jena, Germany
[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
[3] Peking Union Med Coll, Beijing 100050, Peoples R China
关键词
peptides; rakicidin C; natural products; chemical screening; Streptomyces; structure elucidation;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Chemical screening of extracts of Actinomycetes strains has led to the detection, isolation, and structure elucidation of the new cyclic depsipeptide rakicidin C (1). The secondary metabolite from Streptomyces sp. (strain GT 61042) is built-up from glutamine, N-methyl glycine, 4-amino-(2E,4)pentadienoic acid, and 3-hydroxy-2,4,6,8-tetramethylnonanoic acid.
引用
收藏
页码:3353 / 3356
页数:4
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