An NMR Spectral Study of the Structure of 5,5,6-trihydroxy-6-methyldihydropyrimidine-2,4-(1H,3H)-dione in DMSO-d6

被引：1

作者：

Petrova, S. F. ^{[1
]}

Nugumanov, T. R. ^{[1
]}

Lobov, A. N. ^{[1
]}

Spirikhin, L., V ^{[1
]}

Ivanov, S. P. ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Fed Ctr, Ufa Inst Chem, Ufa, Russia

来源：

JOURNAL OF APPLIED SPECTROSCOPY | 2022年 / 89卷 / 02期

关键词：

5; 6-trihydroxy-6-methyldihydropyrimidine-2; 4(1H; 3H)-dione; NMR spectroscopy; dimethyl sulfoxide; EFFICIENT SCAVENGER; 5-HYDROXY-6-METHYLURACIL; OXIDATION;

D O I：

10.1007/s10812-022-01347-z

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The structure of 5,5,6-trihydroxy-6-methyldihydropyrimidine-2,4(1H,3H)-dione (2) was proven using C-13, H-1, and N-15 NMR spectroscopy. A new form (2a) was detected and shown to have a structure similar to dione 2.

引用

页码：225 / 231

页数：7

共 44 条

[21] Solid and solution state NMR spectra and the structure of the gallium citrate complex (NH4)3[Ga(C6H5O7)2]•4H2O
Hawkes, GE
O'Brien, P
Salacinski, H
Motevalli, M
Abrahams, I
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2001, (04) : 1005 - 1011
[22] (3aS,4R,5R,6S,7aR)-4,5-Dibromo-2-[4-(trifluoromethyl)phenyl]-2,3,3a,4,5,6,7,7a-octahydro-3a,6-epoxy-1H-isoindol-1-one: crystal structure and Hirshfeld surface analysis
Mertsalov, Dmitriy F.
Alekseeva, Kseniia A.
Daria, Magrycheva S.
Cheshigin, Maxim E.
Celikesir, Sevim Turktekin
Akkurt, Mehmet
Grigoriev, Mikhail S.
Mlowe, Sixberth
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2021, 77 : 466 - +
[23] Parallel Solid-Phase Synthesis and High-Throughput 1H NMR Evaluation of a 96-Member 1,2,4-Trisubstituted-pyrimidin-6-one-5-carboxylic Acid Library
Hamper, Bruce C.
Kesselring, Allen S.
Chott, Robert C.
Yang, Shengtian
JOURNAL OF COMBINATORIAL CHEMISTRY, 2009, 11 (03): : 469 - 480
[24] Synthesis and structure of osmium complexes: [Ph3PR]2+[OsBr6]2– (R = cyclo-C3H5, n-C4H9, cyclo-C6H11, CH2C(O)Ph), [Ph3PPr]2+[OsBr6]2– ∙ DMSO, and [Ph3P(CH2)3PPh3]2+[OsBr6]2– ∙ DMSO
V. V. Sharutin
O. K. Sharutina
V. S. Senchurin
P. A. Pel’kov
M. I. Kodess
Russian Journal of Coordination Chemistry, 2017, 43 : 97 - 105
[25] Synthesis and structure of osmium complexes: [Ph3PR] 2 + [OsBr6]2- (R = cyclo-C3H5, n-C4H9, cyclo-C6H11, CH2C(O)Ph), [Ph3PPr] 2 + [OsBr6]2- a™ DMSO, and [Ph3P(CH2)3PPh3]2+[OsBr6]2- a™ DMSO
Sharutin, V. V.
Sharutina, O. K.
Senchurin, V. S.
Pel'kov, P. A.
Kodess, M. I.
RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2017, 43 (02) : 97 - 105
[26] Substituted Imidazole of 5-Fluoro-2-[4-[(2-phenyl-1H-imidazol-5yl)methyl]-1-piperazinyl]pyrimidine Inactivates Cytochrome P450 2D6 by Protein Adduction
Nagy, Leslie D.
Mocny, Catherine S.
Diffenderfer, Laura E.
Hsi, David J.
Butler, Brendan F.
Arthur, Evan J.
Fletke, Kyle J.
Palamanda, Jairam R.
Nomeir, Amin A.
Furge, Laura Lowe
DRUG METABOLISM AND DISPOSITION, 2011, 39 (06) : 974 - 983
[27] 6-[(2S,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-5-fluoropyrimidine-4-carbaldehyde
Sousa, Joana L. C.
Albuquerque, Helio M. T.
Silva, Artur M. S.
MOLBANK, 2023, 2023 (01)
[28] Ring-ring isomerization in the series of N-(carbamoyl)-1-aryl-2,3,4,5,6,7-hexahydro-3-hydroxy-6,6-dimethyl-2,4-dioxo-1H-indole-3-carboxamides
Borodkin, G. S.
Zaichenko, S. B.
Borodkina, I. G.
Belousova, L. V.
Ukhin, L. Yu.
RUSSIAN CHEMICAL BULLETIN, 2015, 64 (03) : 664 - 667
[29] The crystal structure of tris(2,3,4,6,7,8,9,10-octahydro-1H-pyrimido[1,2-a]azepin-5-ium) trihydrodecavanadate(V), C27H54N6O28V10
Huo, Yueyang
He, Qingpeng
Wang, Yong
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2021, 236 (02): : 401 - 404
[30] Ring-ring isomerization in the series of N-(carbamoyl)-1-aryl-2,3,4,5,6,7-hexahydro-3-hydroxy-6,6-dimethyl-2,4-dioxo-1H-indole-3-carboxamides
G. S. Borodkin
S. B. Zaichenko
I. G. Borodkina
L. V. Belousova
L. Yu. Ukhin
Russian Chemical Bulletin, 2015, 64 : 664 - 667

← 1 2 3 4 5 →