Neural substrates in secondary somatosensory area for the perception of different tactile sensations

被引:6
作者
Lee, Stephanie D. [1 ,2 ]
Jung, Yujin [1 ]
Chung, Yong An [1 ]
Lee, Wonhye [1 ,2 ]
机构
[1] Catholic Univ Korea, Incheon St Marys Hosp, Inst Catholic Integrat Med, Inchon, South Korea
[2] Harvard Univ, Brigham & Womens Hosp, Dept Radiol, Sch Med, Boston, MA 02115 USA
关键词
human secondary somatosensory area; tactile stimuli; functional MRI; cortical inflation; HUMAN BRAIN; POSTCENTRAL GYRUS; INSULAR CORTEX; CONTACT HEAT; INDEX FINGER; 7; TESLA; STIMULATION; FMRI; PAIN; ACTIVATION;
D O I
10.1002/ima.22160
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
This functional magnetic resonance imaging (fMRI) study investigated the secondary somatosensory area (SII) in humans, especially regarding the presence of distinctive spatial arrangements of neural subunits responding to different types of tactile stimuli. Ten healthy volunteers received four different sensory stimuli on the palmar side of the right handvibrotactile, pressure, warmth, and coolness. Based on group-level analysis of the fMRI data, all four of the somatosensory stimuli resulted in activations in the bilateral SII and insula as well as the SI contralateral to the stimulation. The spatial distribution of neural activations corresponding to each stimulus, as examined by cortical inflation technique, revealed significant overlaps, but also showed the differences in terms of its overall topology. The local maxima of the activation within the SII, corresponding to these stimuli, manifested distinctive spatial location. These results suggest that differential networks of the SII subregions are involved in the processing of the different nature of the tactile stimuli, while sharing common regions in the parietal operculum.
引用
收藏
页码:85 / 91
页数:7
相关论文
共 43 条
[21]  
Hui KKS, 2000, HUM BRAIN MAPP, V9, P13, DOI 10.1002/(SICI)1097-0193(2000)9:1<13::AID-HBM2>3.0.CO
[22]  
2-F
[23]  
IWAMURA Y, 1993, EXP BRAIN RES, V92, P360
[24]   fMRI assessment of somatotopy in human Brodmann area 3b by electrical finger stimulation [J].
Kurth, R ;
Villringer, K ;
Mackert, BM ;
Schwiemann, J ;
Braun, J ;
Curio, G ;
Villringer, A ;
Wolf, KJ .
NEUROREPORT, 1998, 9 (02) :207-212
[25]   fMRI shows multiple somatotopic digit representations in human primary somatosensoy cortex [J].
Kurth, R ;
Villringer, K ;
Curio, G ;
Wolf, KJ ;
Krause, T ;
Repenthin, J ;
Schwiemann, J ;
Deuchert, M ;
Villringer, A .
NEUROREPORT, 2000, 11 (07) :1487-1491
[26]   IMAGE-GUIDED FOCUSED ULTRASOUND-MEDIATED REGIONAL BRAIN STIMULATION IN SHEEP [J].
Lee, Wonhye ;
Lee, Stephanie D. ;
Park, Michael Y. ;
Foley, Lori ;
Purcell-Estabrook, Erin ;
Kim, Hyungmin ;
Fischer, Krisztina ;
Maeng, Lee-So ;
Yoo, Seung-Schik .
ULTRASOUND IN MEDICINE AND BIOLOGY, 2016, 42 (02) :459-470
[27]   Image-Guided Transcranial Focused Ultrasound Stimulates Human Primary Somatosensory Cortex [J].
Lee, Wonhye ;
Kim, Hyungmin ;
Jung, Yujin ;
Song, In-Uk ;
Chung, Yong An ;
Yoo, Seung-Schik .
SCIENTIFIC REPORTS, 2015, 5
[28]   Transcranial focused ultrasound modulates the activity of primary somatosensory cortex in humans [J].
Legon, Wynn ;
Sato, Tomokazu F. ;
Opitz, Alexander ;
Mueller, Jerel ;
Barbour, Aaron ;
Williams, Amanda ;
Tyler, William J. .
NATURE NEUROSCIENCE, 2014, 17 (02) :322-329
[29]   Somatosensory and pain responses to stimulation of the second somatosensory area (SII) in humans.: A comparison with SI and insular responses [J].
Mazzola, L. ;
Isnard, J. ;
Mauguiere, F. .
CEREBRAL CORTEX, 2006, 16 (07) :960-968
[30]   Stimulation of the human cortex and the experience of pain: Wilder Penfield's observations revisited [J].
Mazzola, Laure ;
Isnard, Jean ;
Peyron, Roland ;
Mauguiere, Francois .
BRAIN, 2012, 135 :631-640