Synthesis of aza mono, bi and tricyclic compounds.: Evaluation of their anti MDR activity

被引：44
作者：
Gallo, S
Atifi, S
Mahamoud, A
Santelli-Rouvier, C
Wolfárt, K
Molnar, J
Barbe, J
机构：
[1] Univ Mediterranee, CNRS, UMR 6009, GERCTOP,Fac Pharm, F-13385 Marseille 5, France
[2] Univ Szeged, Inst Microbiol, Szeged, Hungary
来源：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2003年 / 38卷 / 01期
关键词：
P-gp inhibitors; acridinic compounds; pyridoquinolines;
D O I：
10.1016/S0223-5234(02)01422-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Anti MDR activity of a series of acridine, pyridoquinoline, quinoline and pyridine analogous amines was evaluated. Interesting activity is displayed by tricyclic compounds. Besides ring size, influence of the side chain was studied. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码：19 / 26
页数：8
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