IMMUN RESPONSES IN COVID-19

被引：2
作者：
Cakal, Bulent [1 ]
机构：
[1] Istanbul Univ, Istanbul Tip Fak, Tibbi Mikrobiyol Anabilim Dali, Istanbul, Turkey
来源：
JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI | 2021年 / 84卷 / 02期
关键词：
COVID-19; SARS-CoV-2; immunopathology; immune dysregulation; macrophage activation; interleukin-6; cytokine/chemokine storm; hrombo inflammator syndrome;
D O I：
10.26650/IUITFD.2020.0056
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The Coronavirus disease 19 (COVID-19) pandemic, which is the etiological agent of a severe acute respiratory syndrome-associated coronavirus (SARS-CoV- 2), has influenced the whole world with the current and possible results. COVID- 19 has very unique virological, clinical and immunological characteristics. In COVID19, immune responses can vary widely, ranging from responses that allow control of the infection to pulmonary thrombosis characterized by sudden and rapidly developing intense inflammation and storm of cytokenemia. This review aims to examine scientific data about immunopathogenesis of COVID-19
引用
收藏
页码：256 / 263
页数：8
相关论文
共 50 条
  • [1] COVID-19: immunopathology and its implications for therapy
    Cao, Xuetao
    [J]. NATURE REVIEWS IMMUNOLOGY, 2020, 20 (05) : 269 - 270
  • [2] CHANG MG, 2020, NATURE, V201, P1150
  • [3] Chen G., 2020, J CLIN INVEST, V130, P2620, DOI [DOI 10.1172/JCI137244, 10.1172/JCI137244, 10.1101/2020.02.16.20023903]
  • [4] Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records
    Chen, Huijun
    Guo, Juanjuan
    Wang, Chen
    Luo, Fan
    Yu, Xuechen
    Zhang, Wei
    Li, Jiafu
    Zhao, Dongchi
    Xu, Dan
    Gong, Qing
    Liao, Jing
    Yang, Huixia
    Hou, Wei
    Zhang, Yuanzhen
    [J]. LANCET, 2020, 395 (10226) : 809 - 815
  • [5] CHEN W, 2010, J GEN VIROL, V22, P883
  • [6] Ciceri F, 2020, CRIT CARE RESUSC, V22, P95
  • [7] Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)
    Diao, Bo
    Wang, Chenhui
    Tan, Yingjun
    Chen, Xiewan
    Liu, Ying
    Ning, Lifen
    Chen, Li
    Li, Min
    Liu, Yueping
    Wang, Gang
    Yuan, Zilin
    Feng, Zeqing
    Zhang, Yi
    Wu, Yuzhang
    Chen, Yongwen
    [J]. FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [8] A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
    Donoghue, M
    Hsieh, F
    Baronas, E
    Godbout, K
    Gosselin, M
    Stagliano, N
    Donovan, M
    Woolf, B
    Robison, K
    Jeyaseelan, R
    Breitbart, RE
    Acton, S
    [J]. CIRCULATION RESEARCH, 2000, 87 (05) : E1 - E9
  • [9] COVID-19 with Different Severities: A Multicenter Study of Clinical Features
    Feng, Yun
    Ling, Yun
    Bai, Tao
    Xie, Yusang
    Huang, Jie
    Li, Jian
    Xiong, Weining
    Yang, Dexiang
    Chen, Rong
    Lu, Fangying
    Lu, Yunfei
    Liu, Xuhui
    Chen, Yuqing
    Li, Xin
    Li, Yong
    Summah, Hanssa Dwarka
    Lin, Huihuang
    Yan, Jiayang
    Zhou, Min
    Lu, Hongzhou
    Qu, Jieming
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 201 (11) : 1380 - 1388
  • [10] Fogarty H, 2020, BRIT J HAEMATOL, V189, P1060, DOI 10.1111/bjh.16791
12345