SNPmasker: automatic masking of SNPs and repeats across eukaryotic genomes

被引：18

作者：

Andreson, Reidar

Puurand, Tarmo

Remm, Maido

机构：

[1] Univ Tartu, Dept Bioinformat, EE-50090 Tartu, Estonia

[2] Estonian Bioctr, Tartu, Estonia

来源：

NUCLEIC ACIDS RESEARCH | 2006年 / 34卷

关键词：

D O I：

10.1093/nar/gkl125

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

SNPmasker is a comprehensive web interface for masking large eukaryotic genomes. The program is designed to mask SNPs from recent dbSNP database and to mask the repeats with two alternative programs. In addition to the SNP masking, we also offer population- specific substitution of SNP alleles in genomic sequence according toSNP frequencies in HapMap Phase II data. The input to SNP masker can be defined in chromosomal coordinates or inserted as a sequence. The sequences masked by our web server are most useful as a preliminary step for different primer and probe design tasks. The service is available at http://bioinfo.ebc.ee/snpmasker/andis free for all users.

引用

页码：W651 / W655

页数：5

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