Microwave-assisted, solventless Suzuki coupling reactions on palladium-doped alumina

被引:71
作者
Kabalka, GW [1 ]
Pagni, RM
Wang, L
Namboodiri, V
Hair, CM
机构
[1] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA
[2] Univ Tennessee, Dept Radiol, Knoxville, TN 37996 USA
关键词
D O I
10.1039/b001191f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The generation of carbon-carbon bonds forms the backbone of organic synthesis. In recent years, the use of boron-containing precursors in palladium-assisted bond forming reactions (the Suzuki reaction) has gained prominence because of the vast array of functionally substituted boron containing reagents available to the organic chemist. The development of a solventless, microwave-assisted Suzuki reaction utilizing a readily recyclable solid catalyst offers numerous benefits. These include the straightforward recovery of both product and catalyst, conservation of energy through the use of microwave irradiation, simple commercial scale up, and low waste protocols due to the absence of solvents.
引用
收藏
页码:120 / 122
页数:3
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