The effects of galvanic stimulation on the human vestibulo-ocular reflex

被引：14

作者：

Karlberg, M ^{[1
]}

McGarvie, L

Magnusson, M

Aw, ST

Halmagyi, GM

机构：

[1] Royal Prince Alfred Hosp, Dept Neurootol, Sydney, NSW, Australia

[2] Univ Lund Hosp, Dept Otorhinolaryngol, SE-22185 Lund, Sweden

来源：

NEUROREPORT | 2000年 / 11卷 / 17期

关键词：

adult; electric stimulation; eye movements/physiology; galvanic; human; labyrinth; male; vertigo; vestibule/physiology;

D O I：

10.1097/00001756-200011270-00058

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We studied the effects of 5 mA bilateral or unilateral, bipolar or monopolar, galvanic stimulation on the horizontal vestibuloocular reflex (hVOR) in six normal subjects during 0.01, 0.05, 0.1, 0.5 and 1 Hz yaw rotations and in two subjects during high-acceleration, low-amplitude yaw head rotations (head impulses). Bipolar galvanic stimulation induced horizontal nystagmus in all subjects and an asymmetry of the hVOR only during rotations below 0.1 Hz. Monopolar stimulation had no significant effect. The findings suggest that in humans galvanic stimulation affects those primary horizontal semicircular canal neurons that mediate the hVOR via indirect pathways through the velocity storage mechanism. NeuroReport 11:3897-3901 (C) 2000 Lippincott Williams & Wilkins.

引用

页码：3897 / 3901

页数：5

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