Imaging brain activation induced by long trains of repetitive transcranial magnetic stimulation

被引：87

作者：

Siebner, HR

Willoch, F

Peller, M

Auer, C

Boecker, H

Conrad, B

Bartenstein, P

机构：

[1] Tech Univ Munich, Dept Neurol, D-81675 Munich, Germany

[2] Tech Univ Munich, Dept Nucl Med, D-81675 Munich, Germany

来源：

NEUROREPORT | 1998年 / 9卷 / 05期

关键词：

brain activation; FDG-PET; motor cortex; positron emission tomography; rCMRglc; regional cerebral glucose metabolism; repetitive transcranial magnetic stimulation; rTMS;

D O I：

10.1097/00001756-199803300-00033

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

USING positron emission tomography (PET), we measured the relative changes in regional cerebral metabolic rate of glucose (rCMRglc) during 2 Hz repetitive transcranial magnetic stimulation (rTMS) of the left sensorimotor cortex (SM1) and during imitation of rTMS-induced arm movements. Such stimulation caused an rCMRglc increase of about 8% within the SM1. The relative rCMRglc increase within SM1 was significantly greater in magnitude and larger in area during voluntary imitation of rTMS-induced arm movements. Moreover, the rostral part of the SMA was significantly more activated by voluntary movements than during rTMS. Combining rTMS and PET has the potential to visualize rTMS-related net brain activation, and may open up new possibilities for functional network analysis by comparing willed brain activation with electromagnetic brain activation. (C) 1998 Rapid Science Ltd.

引用

页码：943 / 948

页数：6

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