Daptomycin in the treatment of prosthetic joint infection by Enterococcus faecalis: safety and efficacy of high-dose and prolonged therapy

被引：10

作者：

Ramon Yuste, Jose ^{[1
,2
]}

Quesada, Milena ^{[1
]}

Diaz-Rada, Pablo ^{[3
]}

Luis Del Pozo, Jose ^{[1
,4
]}

机构：

[1] Univ Navarra Clin, Div Infect Dis, Pamplona, Spain

[2] Univ Navarra Clin, Dept Internal Med, Pamplona, Spain

[3] Univ Navarra Clin, Dept Orthopaed Surg, Pamplona, Spain

[4] Univ Navarra Clin, Dept Clin Microbiol, Pamplona, Spain

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2014年 / 27卷

关键词：

Daptomycin; Treatment; Prosthetic joint infection; Enterococcus faecalis;

D O I：

10.1016/j.ijid.2014.05.034

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Enterococci are implicated in less than 2.3% of prosthetic joint infections. These infections can be difficult to treat and therapeutic failures are not uncommon. In these situations, daptomycin is a safe and effective alternative. We present a clinical case with a successful response to the prolonged use of high-dose daptomycin. (C) 2014 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

引用

页码：65 / 66

页数：2

共 5 条

[1] Clinical experience with daptomycin for the treatment of patients with knee and hip periprosthetic joint infections [J].

Corona Perez-Cardona, Pablo S. ;

Barro Ojeda, Victor ;

Rodriguez Pardo, Dolors ;

Pigrau Serrallach, Carlos ;

Guerra Farfan, Ernesto ;

Amat Mateu, Carles ;

Flores Sanchez, Xavier .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2012, 67 (07) :1749-1754

[2] Pilot Study of Ampicillin-Ceftriaxone Combination for Treatment of Orthopedic Infections Due to Enterococcus faecalis [J].

Euba, G. ;

Lora-Tamayo, J. ;

Murillo, O. ;

Pedrero, S. ;

Cabo, J. ;

Verdaguer, R. ;

Ariza, J. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (10) :4305-4310

[3] Safety of High-Dose Intravenous Daptomycin Treatment: Three-Year Cumulative Experience in a Clinical Program [J].

Figueroa, D. A. ;

Mangini, E. ;

Amodio-Groton, M. ;

Vardianos, B. ;

Melchert, A. ;

Fana, C. ;

Wehbeh, W. ;

Urban, C. M. ;

Segal-Maurer, S. .

CLINICAL INFECTIOUS DISEASES, 2009, 49 (02) :177-180

[4] Low Rate of Infection Control in Enterococcal Periprosthetic Joint Infections [J].

Rasouli, Mohammad R. ;

Tripathi, Mohan S. ;

Kenyon, Robert ;

Wetters, Nathan ;

Della Valle, Craig J. ;

Parvizi, Javad .

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2012, 470 (10) :2708-2716

[5] The efficacy and safety of daptomycin: first in a new class of antibiotics for Gram-positive bacteria [J].

Rybak, MJ .

CLINICAL MICROBIOLOGY AND INFECTION, 2006, 12 :24-32

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