Germacranolides from Calea urticifolia

被引：29
作者：
Yamada, M
Matsuura, N
Suzuki, H
Kurosaka, C
Hasegawa, N
Ubukata, M
Tanaka, T
Iinuma, M
机构：
[1] Toyama Prefectural Univ, Biotechnol Res Ctr, Toyama 9390398, Japan
[2] Meiji Milk Prod Co Ltd, Dev Sect, Dept Pharmaceut, Shimada Ku, Tokyo 1308502, Japan
[3] Gifu Prefectural Inst Hlth & Environm Sci, Gifu 5040838, Japan
[4] Gifu Pharmaceut Univ, Gifu 5028585, Japan
来源：
PHYTOCHEMISTRY | 2004年 / 65卷 / 23期
关键词：
germacranolides; Calea urticifolia; calealactones; U937; cell; toxicity;
D O I：
10.1016/j.phytochem.2004.08.040
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Four germacranolides, named calealactones A-C and 2,3-epoxycalealactone A, were isolated from the leaves of Calea urticifolia (Compositae) in addition to three known germacranolides. Their structures were established on the basis of spectroscopic analysis including by 2D NMR spectroscopy. Calealactone C and 2,3-epoxyjuanisulamin displayed potent toxicity to U937 cells. (C) 2004 Elsevier Ltd. All rights reserved.
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页码：3107 / 3111
页数：5
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