Novel Syntheses of Some 1, 2, 4-Triazoles as Potent Bacteriocidal Agents

被引：12
作者：
Singh, Ram Janam [1 ]
Singh, Dharmendra Kumar [2 ]
机构：
[1] Indian Oil Corp Ltd, Qual Control Lab, Panipat Refinery, Panipat 132140, Haryana, India
[2] Veer Bahadur Singh Purvanchal Univ, Tilak Dhari Post Grad Coll, Fac Sci, Synthet Res Lab,Dept Chem, Jaunpur 222002, UP, India
来源：
E-JOURNAL OF CHEMISTRY | 2010年 / 7卷 / 01期
关键词：
1; 2; 4-Triazoles; 4-Methylphenyl isothiocyanate; Cyclization; Antibacterial activity; BIOLOGICAL-ACTIVITY;
D O I：
10.1155/2010/168651
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile syntheses of 4-aryl-5-(isomeric pyridoyl)-3H-1, 2, 4-triazoles as potent bacteriocidal agents are described. The newly synthesized compounds were characterized by spectral and elemental analyses. Some compounds were screened for their antibacterial activity against S. aureus, E. coli, B. subtilis and P. aeruginosa. All compounds carrying 1, 2, 4- triazole moiety showed significant biological activity.
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收藏
页码：37 / 40
页数：4
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