Characteristics of peaks in serum concentrations of follicle-stimulating hormone and estradiol, and follicular wave dynamics during the interovulatory interval in cyclic ewes

被引：6
作者：
Toosi, B. M. [1 ]
Seekallu, S. V. [1 ]
Barrett, D. M. W. [1 ]
Davies, K. L. [1 ]
Duggavathi, R. [1 ]
Bagu, E. T. [1 ]
Rawlings, N. C. [1 ]
机构：
[1] Univ Saskatchewan, Western Coll Vet Med, Dept Vet Biomed Sci, Saskatoon, SK S7N 0W0, Canada
来源：
THERIOGENOLOGY | 2010年 / 73卷 / 09期
关键词：
Estradiol; Follicular wave dynamics; Follicle-stimulating hormone; Sheep; ESTROUS-CYCLE; FSH-SECRETION; SUPEROVULATORY RESPONSE; LUTEAL-PHASE; PERIPHERAL CONCENTRATIONS; DIFFERENTIAL REGULATION; ESTRUS SYNCHRONIZATION; NEUROENDOCRINE CONTROL; LUTEINIZING-HORMONE; OVARIAN-STEROIDS;
D O I：
10.1016/j.theriogenology.2009.11.005
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
There are three or four ovarian follicular waves in the interovulatory interval of cyclic ewes Each follicular wave is preceded by a transient peak in serum follicle-stimulating hormone (FSH) concentrations Serum concentrations of estradiol also increase concurrent with the growth of follicle(s) in each wave In the current study, we investigated the patterns of follicular wave development and characteristics of FSH and estradiol peaks in all follicular waves of the interovulatory interval and after induction of a supraphysiologic FSH peak in cyclic ewes (Ovis aris) In Experiment 1, 19 ewes underwent daily ovarian ultrasonography and blood sampling for a complete mterovulatory interval In Experiment 2, seven ewes received two administrations of ovine FSH (oFSH), 8 h apart (1 mu g/kg, sc), at the expected time of the endogenous FSH peak preceding the second follicular wave of the mterovulatory interval. In Experiment 1 the amplitude of the FSH peaks decreased (up to 50%), whereas basal serum FSH concentrations increased across the mterovulatory interval (P < 0 05) Maximum follicular diameter was greater (P < 0 05) for Wave 1 and the Ovulatory wave (6 0 +/- 0 3 and 6 1 +/- 0 2 mm, respectively) than for Waves 2 and 3 (5 3 +/- 0 1 and 5.4 +/- 0 3 mm. respectively). Life span was greater for follicles in Wave 1 compared with other waves (P < 0 05) Treatment with oFSH increased the amplitude of an FSH peak by 5- to 6-fold This treatment increased estradiol production (P < 0 05) but had little effect on other characteristics of the subsequent follicular wave We concluded that changes in the amplitude and duration of the peaks in serum concentrations of FSH that precede follicular waves across the mterovulatory interval do not influence the characteristics of the follicular waves that follow Crown Copyright (c) 2010 Published by Elsevier Inc All rights reserved.
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页码：1192 / 1201
页数：10
相关论文
共 51 条
  • [1] DECAY OF FOLLICLE-STIMULATING HORMONE-BETA MESSENGER-RNA IN THE PRESENCE OF TRANSCRIPTIONAL INHIBITORS AND OR INHIBIN, ACTIVIN, OR FOLLISTATIN
    ATTARDI, B
    WINTERS, SJ
    [J]. MOLECULAR ENDOCRINOLOGY, 1993, 7 (05) : 668 - 680
  • [2] BAIRD DT, 1991, J REPROD FERTIL, P125
  • [3] The repeatability of superovulatory response and embryo recovery in sheep
    Bari, F
    Khalid, M
    Wolf, B
    Haresign, W
    Murray, A
    Merrell, B
    [J]. THERIOGENOLOGY, 2001, 56 (01) : 147 - 155
  • [4] Suppression of follicle wave emergence in cyclic ewes by supraphysiologic concentrations of estradiol-17beta and induction with a physiologic dose of exogenous ovine follicle-stimulating hormone
    Barrett, David M. W.
    Bartlewski, Pawel A.
    Duggavathi, Rajesha
    Davies, Kate L.
    Rawlings, Norman C.
    [J]. BIOLOGY OF REPRODUCTION, 2006, 75 (04) : 633 - 641
  • [5] Ovarian responses, hormonal profiles and embryo yields in anoestrous ewes superovulated with Folltropin®-V after pretreatment with medroxyprogesterone acetate-releasing vaginal sponges and a single dose of oestradiol-17β
    Bartlewski, P. M.
    Alexander, B. D.
    Rawlings, N. C.
    Barrett, D. M. W.
    King, W. A.
    [J]. REPRODUCTION IN DOMESTIC ANIMALS, 2008, 43 (03) : 299 - 307
  • [6] Bartlewski PM, 1999, J REPROD FERTIL, V115, P111, DOI 10.1530/jrf.0.1150111
  • [7] Bartlewski PM, 1998, J REPROD FERTIL, V113, P275, DOI 10.1530/jrf.0.1130275
  • [8] Ovarian antral follicular dynamics and their associations with peripheral concentrations of gonadotropins and ovarian steroids in anoestrous Finnish Landrace ewes
    Bartlewski, PM
    Vanderpol, J
    Beard, AP
    Cook, SJ
    Rawlings, NC
    [J]. ANIMAL REPRODUCTION SCIENCE, 2000, 58 (3-4) : 273 - 291
  • [9] Ovarian function in ewes at the onset of the breeding season
    Bartlewski, PM
    Beard, AP
    Rawlings, NC
    [J]. ANIMAL REPRODUCTION SCIENCE, 1999, 57 (1-2) : 67 - 88
  • [10] An ultrasound-aided study of temporal relationships between the patterns of LH/FSH secretion, development of ovulatory-sized antral follicles and formation of corpora lutea in ewes
    Bartlewski, PM
    Beard, AP
    Rawlings, NC
    [J]. THERIOGENOLOGY, 2000, 54 (02) : 229 - 245
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