Shared Knowledge, Gaps and Challenges of Microdosimetry: Realistic Models of Cells and Endoplasmic Reticulum

被引：0

作者：

Denzi, A. ^{[1
]}

Merla, C. ^{[2
]}

Andre, F. M. ^{[3
]}

Garcia-Sanchez, T. ^{[3
]}

Mir, L. M. ^{[3
]}

Apollonio, F. ^{[1
]}

Liberti, M. ^{[1
]}

机构：

[1] Univ Roma La Sapienza, DIET, Rome, Italy

[2] ENEA, SSPT, Div Hlth Protect Technol, Rome, Italy

[3] Univ Paris Saclay, Univ Paris Sud, CNRS, Villejuif, France

来源：

PROCEEDINGS OF THE 2018 IEEE/MTT-S INTERNATIONAL MICROWAVE BIOMEDICAL CONFERENCE (IMBIOC) | 2018年

关键词：

microdosimetry; electroporation; nanosecond pulses; endoplasmic reticulum; realistically shaped model; THEORETICAL EVALUATION; ELECTRIC-FIELDS; VOLTAGE; PULSES; ENERGY;

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In the study of the biophysical mechanisms at the basis of the EM field interaction leading to biomedical applications, one needs also to know the field strength at the microscopic scale to establish a quantitative relation between the field and the observed effect. Here authors will show the results on the TMP of the plasma membrane and the endoplasmic reticulum (ER) due a 2D realistic shaping of the ER itself, both analysed in the frequency domain and for an electric pulsed field of 10 ns.

引用

页码：19 / 21

页数：3

共 9 条

[1] Microdosimetry for Pulsed E Fields in a Realistic Models of Cells and Endoplasmic Reticulum
Denzi, Agnese
Hanna, Hanna
Andre, Franck M.
Mir, Lluis M.
Apollonio, Francesca
Liberti, Micaela
2017 14TH INTERNATIONAL CONFERENCE ON SYNTHESIS, MODELING, ANALYSIS AND SIMULATION METHODS AND APPLICATIONS TO CIRCUIT DESIGN (SMACD), 2017,
[2] COMPUTATIONAL MODELS OF CALCIUM SIGNALLING IN PANCREATIC ACINAR CELLS SHOW UNIQUE ROLES FOR CALCIUM DIFFUSION IN THE ENDOPLASMIC RETICULUM
Yano, Kojiro
Tepikin, Alexei V.
Petersen, Ole H.
JOURNAL OF PHYSIOLOGICAL SCIENCES, 2009, 59 : 96 - 96
[3] Anomalous Subdiffusion in Living Cells: Bridging the Gap Between Experiments and Realistic Models Through Collaborative Challenges
Woringer, Maxime
Izeddin, Ignacio
Favard, Cyril
Berry, Hugues
FRONTIERS IN PHYSICS, 2020, 8
[4] Skin antigen-presenting cells and wound healing: New knowledge gained and challenges encountered using mouse depletion models
Rajesh, Aarthi
Stuart, Gabriella
Real, Nicola
Tschirley, Allison
Ahn, Jenny
Wise, Lyn
Hibma, Merilyn
IMMUNOLOGY, 2021, 163 (01) : 98 - 104
[5] RETRACTION: Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD (Retraction of Vol 37, art no BSR20170803, 2017)
Tang, Yao
Cai, Qi-Hang
Wang, Yong-Jian
Fan, Shao-Hua
Zhang, Zi-Feng
Xiao, Meng-Qi
Zhu, Jin-Yu
Wu, Dong-Mei
Lu, Jun
Zheng, Yuan-Lin
BIOSCIENCE REPORTS, 2021, 41 (06)
[6] Protective effect of autophagy on endoplasmic reticulum stress-induced apoptosis of alveolar epithelial cells in rat models of COPD (Expression of Concern of Vol 37, art no BSR20170803, 2017)
不详
BIOSCIENCE REPORTS, 2020, 40
[7] Signal Integration of Endoplasmic Reticulum and Mitochondrial Unfolded Protein Stress Responses in Intestinal Epithelial Cells of Patients with Ulcerative Colitis and Murine Models of Immune- Mediated Colitis: Inhibitory Mechanisms of Interleukin 10
Messlik, Anja
Rath, Eva
Berger, Emanuel
Fromme, Tobias
Klingenspor, Martin
Hoogenraad, Nick
Kim, Sandra C.
Liu, Bo
Sartor, R. Balfour
Haller, Dirk
GASTROENTEROLOGY, 2009, 136 (05) : A700 - A700
[8] Decursin Induces G1 Cell Cycle Arrest and Apoptosis through Reactive Oxygen Species-Mediated Endoplasmic Reticulum Stress in Human Colorectal Cancer Cells in In Vitro and Xenograft Models
Kim, Danbee
Go, Seok-Ho
Song, Yeeun
Lee, Dong-Keon
Park, Jeong-Ran
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (18)
[9] RETRACTED: Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD (Publication with Expression of Concern. See vol. 40, 2020) (Retracted article. See vol. 41, 2021)
Tang, Yao
Cai, Qi-Hang
Wang, Yong-Jian
Fan, Shao-Hua
Zhang, Zi-Feng
Xiao, Meng-Qi
Zhu, Jin-Yu
Wu, Dong-Mei
Lu, Jun
Zheng, Yuan-Lin
BIOSCIENCE REPORTS, 2017, 37

← 1 →