The Effects of Medical Diagnostic Low Dose X-rays after in vitro Exposure of Human Red Blood Cells: Hemolysis and Osmotic Fragility

被引：7
作者：
Tungjai, Montree [1 ]
Sopapang, Jetchada [1 ]
Tasri, Natdanai [1 ]
Osothsongkroh, Chanatip [1 ]
Jantarato, Attapon [1 ]
Kothan, Suchart [1 ]
机构：
[1] Chiang Mai Univ, Fac Associated Med Sci, Dept Radiol Technol, Chiang Mai 50200, Thailand
来源：
TOXICOLOGY AND ENVIRONMENTAL HEALTH SCIENCES | 2019年 / 11卷 / 03期
关键词：
Radiation effects; Low-dose radiation; Medical X-rays; Hemolysis; Osmotic fragility; BONE-MARROW-CELLS; NEOPLASTIC TRANSFORMATION; GENOMIC-INSTABILITY; IONIZING-RADIATION; ADAPTIVE RESPONSE; HUMAN-LYMPHOCYTES; GAMMA-RAYS; ENERGY; LEVEL;
D O I：
10.1007/s13530-019-0409-1
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Although low dose X-rays are widely used in medical radiology, the harmful effects of exposure to low dose X-rays during diagnostic radiological examination is still a commonly discussed topic. Objective In this current study, we investigated the effects of medical diagnostic low dose X-rays after an in vitro exposure of human red blood cells. Methods We gave red blood cells an in vitro exposure to a total dose of 0.03, 0.05, and 0.1 mGy of medical diagnostic X-rays. Non-irradiated cells served as the control group. Hemolysis and osmotic fragility tests were used to determine the effects of medical diagnostic low dose X-rays at 10, 30, and 60 min post-irradiation. Results The results indicated no changes in the percentage of hemolysis and osmotic fragility parameters in red blood cells exposed to these low dose X-rays, when compared to the corresponding non-irradiated red blood cells at all harvest time-points. Conclusion These finding suggested that there were no harmful effects of the diagnostic low dose X-rays in an in vitro exposure of human red blood cells.
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收藏
页码：237 / 243
页数：7
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