Comparative Effects of Platelet-Rich Plasma, Platelet Lysate, and Fetal Calf Serum on Mesenchymal Stem Cells

被引：11

作者：

Lykov, A. P. ^{[1
,2
]}

Bondarenko, N. A. ^{[1
,2
]}

Surovtseva, M. A. ^{[1
,2
]}

Kim, I. I. ^{[1
,2
]}

Poveshchenko, O. V. ^{[1
,2
]}

Pokushalov, E. A. ^{[1
,2
]}

Konenkov, V. I. ^{[1
]}

机构：

[1] Minist Hlth Russian Federat, Res Inst Clin & Expt Lymphol, Novosibirsk, Russia

[2] Minist Hlth Russian Federat, EN Meshalkin Novosibirsk Res Inst Circulat Pathol, Novosibirsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2017年 / 163卷 / 06期

关键词：

platelet-rich plasma; platelet lysate; mesenchymal stem cells; proliferation; migration; STROMAL CELLS; IN-VITRO; THERAPIES; GROWTH;

D O I：

10.1007/s10517-017-3897-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied the effects of human platelet-rich plasma and platelet lysate on proliferation, migration, and colony-forming properties of rat mesenchymal stem cells. Platelet-rich plasma and platelet lysate stimulated the proliferation, migration, and colony formation of mesenchymal stem cells. A real-time study showed that platelet-rich plasma produces the most potent stimulatory effect, while both platelet-rich plasma and platelet lysate stimulated migration of cells.

引用

页码：757 / 760

页数：4

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