Synthesis of blood group Forssman pentasaccharide GalNAcα1-3GalNAcβ1-3Galα1-4Galβ1-4Glcβ-R

被引：2

作者：

Popova, Inna S. ^{[1
]}

Korchagina, Elena Yu. ^{[1
]}

Sablina, Marina A. ^{[1
]}

Paramonov, Alexander S. ^{[1
]}

Hult, Annika K. ^{[2
]}

Henry, Stephen M. ^{[3
]}

Bovin, Nicolai V. ^{[1
,3
]}

机构：

[1] Russian Acad Sci, MM Shemyakin Yu A Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia

[2] Lund Univ, Dept Lab Med, Div Hematol & Transfus Med, SE-22184 Lund, Sweden

[3] Auckland Univ Technol, Sch Engn Comp & Math Sci, Auckland 1010, New Zealand

来源：

MENDELEEV COMMUNICATIONS | 2019年 / 29卷 / 05期

基金：

俄罗斯科学基金会;

关键词：

D O I：

10.1016/j.mencom.2019.09.034

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis of the glycan part of Forssman glycolipid GalNAc alpha 1-3GalNAc beta 1-3Gal alpha 1-4Gal beta 1-4Glc-Cer in the form of 2-aminoethyl glycoside has been carried out. The glycoside has been converted into a lipophilic derivative capable of controlled inserting into erythrocytes. The obtained surface-modified cells, termed kodecytes, revealed a high level of the blood group system FORS serological activity.

引用

页码：578 / 580

页数：3