Synthesis of blood group Forssman pentasaccharide GalNAcα1-3GalNAcβ1-3Galα1-4Galβ1-4Glcβ-R

被引：2
作者：
Popova, Inna S. [1 ]
Korchagina, Elena Yu. [1 ]
Sablina, Marina A. [1 ]
Paramonov, Alexander S. [1 ]
Hult, Annika K. [2 ]
Henry, Stephen M. [3 ]
Bovin, Nicolai V. [1 ,3 ]
机构：
[1] Russian Acad Sci, MM Shemyakin Yu A Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
[2] Lund Univ, Dept Lab Med, Div Hematol & Transfus Med, SE-22184 Lund, Sweden
[3] Auckland Univ Technol, Sch Engn Comp & Math Sci, Auckland 1010, New Zealand
来源：
MENDELEEV COMMUNICATIONS | 2019年 / 29卷 / 05期
基金：
俄罗斯科学基金会;
关键词：
D O I：
10.1016/j.mencom.2019.09.034
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis of the glycan part of Forssman glycolipid GalNAc alpha 1-3GalNAc beta 1-3Gal alpha 1-4Gal beta 1-4Glc-Cer in the form of 2-aminoethyl glycoside has been carried out. The glycoside has been converted into a lipophilic derivative capable of controlled inserting into erythrocytes. The obtained surface-modified cells, termed kodecytes, revealed a high level of the blood group system FORS serological activity.
引用
收藏
页码：578 / 580
页数：3
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