Effect of nano/micro-Ag compound particles on the bio-corrosion, antibacterial properties and cell biocompatibility of Ti-Ag alloys

被引:115
作者
Chen, Mian [1 ]
Yang, Lei [1 ]
Zhang, Lan [2 ]
Han, Yong [2 ]
Lu, Zheng [1 ]
Qin, Gaowu [1 ]
Zhang, Erlin [1 ]
机构
[1] Northeastern Univ, Sch Mat Sci & Engn, Key Lab Anisotropy & Texture Mat ATM, Educ Minist China, Shenyang 110819, Peoples R China
[2] Xi An Jiao Tong Univ, State Key Lab Mech Behav Mat, Xian 710049, Peoples R China
来源
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2017年 / 75卷
关键词
Antibacterial property; Biocompatibility; Corrosion resistance; Mechanical property; Ti-Ag alloy; TITANIUM-SILVER ALLOYS; MECHANICAL-PROPERTIES; IN-VITRO; ANTIMICROBIAL ACTIVITY; STAINLESS-STEEL; NANOPARTICLES; CYTOCOMPATIBILITY; RESISTANCE; BEHAVIOR; BACTERIAL;
D O I
10.1016/j.msec.2017.02.142
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
In this research, Ti-Ag alloys were prepared by powder metallurgy, casting and heat treatment method in order to investigate the effect of Ag compound particles on the bio-corrosion, the antibacterial property and the cell biocompatibility. Ti-Ag alloys with different sizes of Ag or Ag-compounds particles were successfully prepared: small amount of submicro-scale (100 nm) Ti2Ag precipitates with solid solution state of Ag, large amount of nano-scale (20-30 nm) Ti2Ag precipitates with small amount of solid solution state of Ag and micro-scale lamellar Ti2Ag phases, and complete solid solution state of Ag. The mechanical tests indicated that both nano/micro-scale Ti2Ag phases had a strong dispersion strengthening ability and Ag had a high solid solution strengthening ability. Electrochemical results shown the Ag content and the size of Ag particles had a limited influence on the biocorrosion resistance although nano-scale Ti2Ag precipitates slightly improved corrosion resistance. It was demonstrated that the nano Ag compounds precipitates have a significant influence on the antibacterial properties of Ti-Ag alloys but no effect on the cell biocompatibility. It was thought that both Ag ions release and Ti2Ag precipitates contributed to the antibacterial ability, in which nano-scale and homogeneously distributed Ti2Ag phases would play a key role in antibacterial process. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:906 / 917
页数:12
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