Properties and Applications of PDMS for Biomedical Engineering: A Review

被引：387

作者：

Miranda, Ines ^{[1
]}

Souza, Andrews ^{[2
]}

Sousa, Paulo ^{[1
]}

Ribeiro, Joao ^{[3
]}

Castanheira, Elisabete M. S. ^{[4
]}

Lima, Rui ^{[2
,5
]}

Minas, Graca ^{[1
]}

机构：

[1] Univ Minho, Ctr MicroElectromech Syst CMEMS UMinho, Campus Azurem, P-4800058 Guimaraes, Portugal

[2] Univ Minho, Mech Engn Dept, MEtRICs, Campus Azurem, P-4800058 Guimaraes, Portugal

[3] Inst Politecn Braganca, Ctr Invest Montanha CIMO, Campus Santa Apolonia, P-5300253 Braganca, Portugal

[4] Univ Minho, Ctr Phys Minho & Porto Univ CF UM UP, Campus Gualtar, P-4710057 Braga, Portugal

[5] Univ Porto FEUP, CEFT, Fac Engn, Rua Roberto Frias, P-4200465 Porto, Portugal

来源：

JOURNAL OF FUNCTIONAL BIOMATERIALS | 2022年 / 13卷 / 01期

关键词：

polydimethylsiloxane; PDMS properties; PDMS applications; microfluidics; biomedical engineering; INTRACRANIAL ANEURYSM MODEL; RED-BLOOD-CELLS; SURFACE MODIFICATION; OXYGEN PLASMA; MICROFLUIDIC DEVICES; CIRCULAR MICROCHANNELS; MECHANICAL-PROPERTIES; POLYDIMETHYLSILOXANE; FABRICATION; POLY(DIMETHYLSILOXANE);

D O I：

10.3390/jfb13010002

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and mechanical properties, which makes it well-suited for several engineering applications. Due to its biocompatibility, PDMS is widely used for biomedical purposes. This widespread use has also led to the massification of the soft-lithography technique, introduced for facilitating the rapid prototyping of micro and nanostructures using elastomeric materials, most notably PDMS. This technique has allowed advances in microfluidic, electronic and biomedical fields. In this review, an overview of the properties of PDMS and some of its commonly used treatments, aiming at the suitability to those fields' needs, are presented. Applications such as microchips in the biomedical field, replication of cardiovascular flow and medical implants are also reviewed.

引用

页数：20

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