Directed Self-Assembly of Dipeptides to Form Ultrathin Hydrogel Membranes

被引：108

作者：

Johnson, Eleanor K. ^{[1
]}

Adams, Dave J. ^{[2
]}

Cameron, Petra J. ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 14期

基金：

英国工程与自然科学研究理事会;

关键词：

SURFACE-PLASMON RESONANCE; QUANTUM DOTS; PEPTIDE; FILMS; IMMOBILIZE; ORGANOGELS; BINDING; ENZYME;

D O I：

10.1021/ja909579p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The dipeptide amphiphile Fmoc-Leu-Gly-OH has been induced to self-assemble into thin surface-supported hydrogel gel films and gap-spanning hydrogel membranes. The thickness can be closely controlled, giving films/membranes from tens of nanometers to millimeters thick. SEM and TEM have confirmed that the dipeptides self-assemble to form fibers, with the membranes resembling a dense "mat" of entangled fibers. The films and membranes were stable once formed. The films could be reversibly dried and collapsed, then reswollen to regain the gel structure.

引用

页码：5130 / 5136

页数：7

共 44 条

[1] Relationship between molecular structure, gelation behaviour and gel properties of Fmoc-dipeptides [J].

Adams, Dave J. ;

Mullen, Leanne M. ;

Berta, Marco ;

Chen, Lin ;

Frith, William J. .

SOFT MATTER, 2010, 6 (09) :1971-1980

[2] A new method for maintaining homogeneity during liquid-hydrogel transitions using low molecular weight hydrogelators [J].

Adams, Dave J. ;

Butler, Michael F. ;

Frith, William J. ;

Kirkland, Mark ;

Mullen, Leanne ;

Sanderson, Paul .

SOFT MATTER, 2009, 5 (09) :1856-1862

[3]

[Anonymous], CRC HDB CHEM PHYS

[4] Pentapeptide based organogels: the role of adjacently located phenylalanine residues in gel formation [J].

Banerjee, Arijit ;

Palui, Goutam ;

Banerjee, Arindam .

SOFT MATTER, 2008, 4 (07) :1430-1437

[5] Interfacing Supramolecular Gels and Quantum Dots with Ultrasound: Smart Photoluminescent Dipeptide Gels [J].

Bardelang, David ;

Zaman, Md. Badruz ;

Moudrakovski, Igor L. ;

Pawsey, Shane ;

Margeson, James C. ;

Wang, Dashan ;

Wu, Xiaohua ;

Ripmeester, John A. ;

Ratcliffe, Christopher I. ;

Yu, Kui .

ADVANCED MATERIALS, 2008, 20 (23) :4517-4520

[6] A new class of thin film hydrogels produced by plasma polymerization [J].

Bhattacharyya, Dhiman ;

Pillai, Karthikeyan ;

Chyan, Oliver M. R. ;

Tang, Liping ;

Timmons, Richard B. .

CHEMISTRY OF MATERIALS, 2007, 19 (09) :2222-2228

[7] Optical waveguide spectroscopy study of the transport and binding of cytochrome c in mesoporous titanium dioxide electrodes [J].

Cameron, Petra J. ;

Jenkins, A. Toby A. ;

Knoll, Wolfgang ;

Marken, Frank ;

Milsom, Elizabeth V. ;

Williams, Tom L. .

JOURNAL OF MATERIALS CHEMISTRY, 2008, 18 (36) :4304-4310

[8] Monitoring the covalent binding of quantum dots to functionalized gold surfaces by surface plasmon resonance spectroscopy [J].

Cameron, Petra J. ;

Zhong, Xinhua ;

Knoll, Wolfgang .

JOURNAL OF PHYSICAL CHEMISTRY C, 2007, 111 (28) :10313-10319

[9]

CHEN L, 2010, LANGMUIR, DOI DOI 10.1021/1A903694A

[10] Electrochemically directed synthesis of oligonucleotides for DNA microarray fabrication [J].

Egeland, RD ;

Southern, EM .

NUCLEIC ACIDS RESEARCH, 2005, 33 (14) :1-7

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