A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference (vol 33, pg 401, 2003)

被引:7
作者
Rubinson, Douglas A.
Dillon, Christopher P.
Kwiatkowski, Adam V.
Sievers, Claudia
Yang, Lili
Kopinja, Johnny
Zhang, Mingdi
McManus, Michael T.
Gertler, Frank B.
Scott, Martin L.
Van Parijs, Luk
机构
关键词
D O I
10.1038/ng0607-803
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Nat. Genet 33, 401–406 (2003); published online 18 February 2003; corrected after print 14 May 2007 The authors wish to remove panels b, d and e of Figure 2 because they were falsified or fabricated. Figure 2 shows the functional silencing of genes in primary cells by lentiviral-mediated RNAi. The authors showed that primary activated T cells can be successfully transduced by lentivirus and that RNAi-targeted surface markers are downregulated in transduced cells (Fig.
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页码:803 / 803
页数:1
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[1]   A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference [J].
Rubinson, DA ;
Dillon, CP ;
Kwiatkowski, AV ;
Sievers, C ;
Yang, LL ;
Kopinja, J ;
Zhang, MD ;
McManus, MT ;
Gertler, FB ;
Scott, ML ;
Van Parijs, L .
NATURE GENETICS, 2003, 33 (03) :401-406