Approaches to the assessment of severe asthma: barriers and strategies

被引:32
作者
Majellano, Eleanor C. [1 ,2 ,3 ]
Clark, Vanessa L. [1 ,2 ,3 ]
Winter, Natasha A. [1 ,2 ,4 ]
Gibson, Peter G. [1 ,2 ,5 ]
McDonald, Vanessa M. [1 ,2 ,3 ,5 ]
机构
[1] Univ Newcastle, Natl Hlth & Med Res Council, Ctr Res Excellence Severe Asthma, Newcastle, NSW, Australia
[2] Univ Newcastle, Prior Res Ctr Hlth Lungs, Newcastle, NSW, Australia
[3] Univ Newcastle, Fac Hlth & Med, Sch Nursing & Midwifery, Newcastle, NSW, Australia
[4] Univ Newcastle, Fac Hlth & Med, Sch Med & Publ Hlth, Newcastle, NSW, Australia
[5] John Hunter Hosp, Hunter Med Res Inst, Dept Resp & Sleep Med, Newcastle, NSW, Australia
基金
英国医学研究理事会;
关键词
asthma; severe asthma; severity; assessment; barriers; strategies; NITRIC-OXIDE MEASUREMENTS; PRIMARY-CARE; MULTIDIMENSIONAL ASSESSMENT; AIRWAY INFLAMMATION; BLOOD EOSINOPHILS; SPUTUM EOSINOPHIL; MANAGEMENT; COMMUNICATION; BIOMARKERS; PERIOSTIN;
D O I
10.2147/JAA.S178927
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Asthma is a chronic condition with great variability. It is characterized by intermittent episodes of wheeze, cough, chest tightness, dyspnea and backed by variable airflow limitation, airway inflammation and airway hyper-responsiveness. Asthma severity varies uniquely between individuals and may change over time. Stratification of asthma severity is an integral part of asthma management linking appropriate treatment to establish asthma control. Precision assessment of severe asthma is crucial for monitoring the health of people with this disease. The literature suggests multiple factors that impede the assessment of severe asthma, these can be grouped into health care professional, patient and organizational related barriers. These barriers do not exist in isolation but interact and influence one another. Recognition of these barriers is necessary to promote precision in the assessment and management of severe asthma in the era of targeted therapy. In this review, we discuss the current knowledge of the barriers that impede assessment in severe asthma and recommend potential strategies for overcoming these barriers. We highlight the relevance of multidimensional assessment as an ideal approach to the assessment and management of severe asthma.
引用
收藏
页码:235 / 251
页数:17
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