Sleep disorders in Parkinson's disease: insomnia and sleep fragmentation, daytime hypersomnia, alterations to the circadian rhythm and sleep apnea syndrome

被引：0

作者：

Mondragon-Rezola, Elisabet ^{[1
]}

Arratibel-Echarren, Izaskun ^{[1
]}

Ruiz-Martinez, Javier ^{[1
]}

Felix Marti-Masso, Jose ^{[1
]}

机构：

[1] Hosp Donostia, Serv Neurol, P Doctor Beguiristain S-N, E-20014 San Sebastian, Guipuzcoa, Spain

来源：

REVISTA DE NEUROLOGIA | 2010年 / 50卷

关键词：

Circadian rhythm; Insomnia; Parkinson's disease; Pathophysiology; Sleep apnea; Sleep disorders; Sleepiness;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction. Sleep disorders in Parkinson's disease are present in 60-98% of patients and reduce their quality of life. Aims. To review the pathophysiology, diagnostic approach and management of the different sleep disorders. Development. We describe the pathophysiology associated with neurodegeneration, due to symptoms (motor and nonmotor) and drug therapies. This article reviews insomnia, excessive daytime sleepiness, circadian sleep disorders and sleep apnea. Conclusions. Subjective or objective sleepiness assessment should routinely be performed by physicians looking after Parkinson's disease patients. Management is difficult and should be targeted to the specific sleep disorder and its likely cause.

引用

页码：S21 / S26

页数：6

共 46 条

[1] Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson's disease [J].