In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia

被引:19
作者
Jackson, W. [1 ]
Hornik, C. P. [2 ,3 ]
Messina, J. A. [2 ]
Guglielmo, K. [2 ]
Watwe, A. [2 ]
Delancy, G. [2 ]
Valdez, A. [2 ]
MacArthur, T. [2 ]
Peter-Wohl, S. [1 ]
Smith, P. B. [2 ,3 ]
Tolia, V. N. [4 ]
Laughon, M. M. [1 ]
机构
[1] Univ North Carolina Chapel Hill, Dept Pediat, Chapel Hill, NC USA
[2] Duke Univ, Med Ctr, Duke Clin Res Inst, Durham, NC USA
[3] Duke Univ, Med Ctr, Dept Pediat, Durham, NC USA
[4] Pediat Obstet Ctr Res & Educ, Sunrise, FL USA
基金
美国国家卫生研究院;
关键词
PRETERM INFANTS; RESPIRATORY OUTCOMES; CAFFEINE THERAPY; NASAL CANNULAE; NICU DISCHARGE; CARE; DEFINITION; CHILDREN; AGE;
D O I
10.1038/jp.2017.49
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: To characterize in-hospital outcomes of premature infants diagnosed with severe bronchopulmonary dysplasia (BPD). STUDY DESIGN: Retrospective cohort study including premature infants with severe BPD discharged from 348 Pediatrix Medical Group neonatal intensive care units from 1997 to 2015. RESULTS: There were 10 752 infants with severe BPD, and 549/10 752 (5%) died before discharge. Infants who died were more likely to be male, small for gestational age, have received more medical interventions and more frequently diagnosed with surgical necrotizing enterocolitis, culture-proven sepsis and pulmonary hypertension following 36 weeks Of postmenstrual age compared with survivors. Approximately 70% of infants with severe BPD were discharged by 44 weeks of postmenstrual age, and 86% were discharged by 48 weeks of postmenstrual age. CONCLUSIONS: A majority of infants diagnosed with severe BPD were discharged home by 44 weeks of postmenstrual age. These results may inform discussions with families regarding the expected hospital course of infants diagnosed with severe BPD. published online 6 April 2017
引用
收藏
页码:853 / 856
页数:4
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