In patients with stroke or TIA and CYP2C19 loss-of-function alleles, ticagrelor vs. clopidogrel reduced 90-d stroke

被引：1
|
作者：
Joundi, Raed A. [1 ]
机构：
[1] McMaster Univ, Hamilton, ON, Canada
来源：
ANNALS OF INTERNAL MEDICINE | 2022年 / 175卷 / 03期
关键词：
MINOR STROKE; ASPIRIN;
D O I：
10.7326/J22-0008
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：JC30 / JC30
页数：1
相关论文
共 36 条
  • [21] Pharmacogenetics of CYP2C19 genetic polymorphism on clopidogrel response in patients with ischemic stroke from Saudi Arabia
    Alhazzani, Adel A.
    Munisamy, Murali
    Karunakaran, Gauthaman
    NEUROSCIENCES, 2017, 22 (01) : 31 - 37
  • [22] Baseline P2Y12 reactivity, kidney function, and CYP2C19 genotype determine clopidogrel responsiveness in acute stroke
    Lee, Yi-Chung
    Liao, Yi-Chu
    Lin, Chun-Jen
    Chung, Chih-Ping
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [23] Optimizing Choice of Dual Antiplatelet Therapy in CYP2C19 Loss-of-Function Carriers
    Brown, Tiffany
    Gonzales, Nicole
    NEUROLOGY, 2023, 100 (05) : 223 - 224
  • [24] Concomitant Use of Proton-Pump Inhibitors and Clopidogrel Increases the Risk of Adverse Outcomes in Patients With Ischemic Stroke Carrying Reduced-Function CYP2C19*2
    Yi, Xingyang
    Han, Zhao
    Zhou, Qiang
    Cheng, Wen
    Lin, Jing
    Wang, Chun
    CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2018, 24 (01) : 55 - 62
  • [25] Relationship between CYP2C19 Polymorphism and Clopidogrel Resistance in Patients with Coronary Heart Disease and Ischemic Stroke in China
    Chang, Rong
    Zhou, Wenqin
    Ye, Yi
    Zhang, Xiaofei
    Liu, Yanmin
    Wu, Jinchun
    GENETICS RESEARCH, 2022, 2022
  • [26] METTL3-mediated methylation of CYP2C19 mRNA may aggravate clopidogrel resistance in ischemic stroke patients
    Tan, Quandan
    Yang, Le
    Yuan, Shanshan
    Zheng, Danni
    Lin, Yapeng
    Chen, Kejie
    He, Ying
    Chen, Shuntian
    Hao, Junli
    Dai, Jin
    He, Song
    Mao, Fengkai
    Leng, Xinyi
    Jiang, Haisong
    Yang, Jie
    OPEN MEDICINE, 2024, 19 (01):
  • [27] Impact of CYP2C19 polymorphism in prognosis of minor stroke or TIA patients with declined eGFR on dual antiplatelet therapy: CHANCE substudy
    Wu, Yu
    Zhou, Yilun
    Pan, Yuesong
    Zhao, Xingquan
    Liu, Liping
    Wang, David
    Wang, Chunxue
    Li, Hao
    Johnston, S. Claiborne
    Meng, Xia
    Wang, Yilong
    Wang, Yongjun
    PHARMACOGENOMICS JOURNAL, 2018, 18 (06) : 713 - 720
  • [28] Interaction of CYP2C19, P2Y12, and GPIIIa Variants Associates With Efficacy of Clopidogrel and Adverse Events on Patients With Ischemic Stroke
    Yi, Xingyang
    Wang, Yanfen
    Lin, Jing
    Cheng, Wen
    Zhou, Qiang
    Wang, Chun
    CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2017, 23 (07) : 761 - 768
  • [29] Does CYP2C19 polymorphisms affect neurological deterioration in stroke/TIA patients? A systematic review and meta-analysis of prospective cohort studies
    Wang, Jiajing
    Kuang, Jie
    Yi, Yingping
    Peng, Chen
    Ge, Yanqiu
    Yin, Shujuan
    Zhang, Xiaolin
    Chen, Jibiao
    MEDICINE, 2021, 100 (11) : E25150
  • [30] Should CYP2C19 Genotyping Be Recommended as a Straight Forward Approach to Optimize Clopidogrel Utilization in Patients with Ischemic Stroke Complicated by Type 2 Diabetes Mellitus?
    Sun, Jialin
    Leng, Ping
    Sun, Chen
    Xu, Wen
    Zhao, Zhenhuan
    Li, Xiao
    Zhang, Xiaolei
    Li, Jing
    PHARMACOGENOMICS & PERSONALIZED MEDICINE, 2020, 13 : 645 - 653
1234