Clinical Characteristics and Predictors Related to the Progression of Multinodular Goiter Causing Tracheal Compression and Deviation: A Report of Two Cases and Review of the Literature

被引：2

作者：

Takamori, Toshihiro ^{[1
]}

Izawa, Shoichiro ^{[2
]}

Fukuhara, Takahiro ^{[3
]}

Sato, Akemi ^{[1
]}

Ichikawa, Hitomi ^{[1
]}

Motokura, Toru ^{[4
]}

Yamamoto, Kazuhiro ^{[2
]}

Fukuda, Tetsuya ^{[1
]}

机构：

[1] Tottori Univ Hosp, Div Clin Lab, Yonago, Tottori, Japan

[2] Tottori Univ, Fac Med, Div Endocrinol & Metab, Yonago, Tottori, Japan

[3] Tottori Univ, Fac Med, Dept Otolaryngol Head & Neck Surg, Yonago, Tottori, Japan

[4] Tottori Univ, Fac Med, Div Clin Lab Med, Yonago, Tottori, Japan

来源：

INTERNAL MEDICINE | 2022年 / 61卷 / 09期

关键词：

multinodular goiter; tracheal compression; tracheal deviation; thyroglobulin; hyperthyroidism; DIFFERENTIATED THYROID-CANCER; ACUTE RESPIRATORY-FAILURE; MANAGEMENT GUIDELINES; SERUM THYROGLOBULIN; AIRWAY-OBSTRUCTION; NODULAR GOITER; ASSOCIATION; THERAPY; FLOW;

D O I：

10.2169/internalmedicine.7989-21

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe the clinical course of two patients who developed tracheal compression and deviation by multinodular goiter (MNG). Case 1: A 66-year-old woman presented with thyroid swelling. Five years after the initial admission, she was diagnosed with hyperthyroidism by Graves??? disease and increased bilateral thyroid lobes compressing the trachea. Thyroglobulin was elevated from 210 to 472 ng/mL. Case 2: A 52-yearold woman presented with thyroid swelling. Five years after the initial admission, the increased right lobe deviated the trachea and compressed the right recurrent laryngeal nerve. Thyroglobulin was elevated from 122 to 392 ng/mL. Two cases and literature review indicated that MNG with >50 mm, solid components, and extension to the mediastinum or paralarynx were risk factors of tracheal compression and deviation. Monitoring thyroglobulin elevation can help predict the clinical course.

引用

页码：1375 / 1381

页数：7

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