Prognosis in Myelodysplastic Syndromes: The Clinical Challenge of Genomic Integration

被引：3

作者：

Chen-Liang, Tzu-Hua ^{[1
]}

机构：

[1] Univ Hosp Morales Meseguer, Hematol & Oncol Unit, Marques Los Velez S-N, Murcia 30008, Spain

来源：

JOURNAL OF CLINICAL MEDICINE | 2021年 / 10卷 / 10期

关键词：

prognostic impact; clinical– genetic alterations; myelodysplastic syndrome; ACUTE MYELOID-LEUKEMIA; SCORING SYSTEM; SETBP1; MUTATIONS; SOMATIC MUTATIONS; ALLELE FREQUENCY; SF3B1; MUTATION; TP53; MUTANT CLONES; RISK; IMPACT;

D O I：

10.3390/jcm10102052

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic neoplasms characterized by ineffective hematopoiesis and myelodysplasia with a variable spectrum of clinical-biological features that can be used to build a prognostic estimation. This review summarizes the current most widely used prognostic scoring systems and gives a general view of the prognostic impact of somatic mutations in MDS patients.

引用

页数：11

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