Cryptococcal meningitis in a patient treated with infliximab

被引:28
作者
Munoz, Patricia
Giannella, Maddalena
Valerio, Maricela
Soria, Teresa
Diaz, Fernando
Longo, Javier Lopez
Bouza, Emilio
机构
[1] Univ Madrid, Hosp Gen Gregorio Maranon, Dept Clin Microbiol & Infect Dis, E-28007 Madrid, Spain
[2] Univ Roma La Sapienza, Policlin Umberto I, Dept Clin Med, Rome, Italy
[3] Univ Madrid, Hosp Gen Gregorio Maranon, Dept Neurol, E-28007 Madrid, Spain
[4] Univ Madrid, Hosp Gen Gregorio Maranon, Dept Rheumatol, E-28007 Madrid, Spain
关键词
infliximab; Cryptococcus neoformans; rheumatoid arthritis; immunosuppressed host; meningitis; pneumonia;
D O I
10.1016/j.diagmicrobio.2006.10.014
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Infliximab, a tumor necrosis factor-alpha inhibitor, is increasingly used for the therapy of different inflammatory conditions. We report the first case of cryptococcal meningitis in a patient treated with infliximab and other immunosuppressive agents, and review a further 5 reported cryptococcal infections. All of them involved fungal pneumonia. Outcome was favorable in all cases. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:443 / 446
页数:4
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