ncRNAs regulate bovine adipose tissue deposition

被引:14
|
作者
Lei, Zhaoxiong [1 ,2 ]
Wu, Huiguang [3 ]
Xiong, Yan [4 ]
Wei, Dawei [1 ,2 ]
Wang, Xingping [1 ,2 ]
Luoreng, Zhuoma [1 ,2 ]
Cai, Xiaoyan [1 ,2 ]
Ma, Yun [1 ,2 ,5 ]
机构
[1] Ningxia Univ, Sch Agr, Yinchuan, Ningxia, Peoples R China
[2] Ningxia Univ, Key Lab Ruminant Mol & Cellular Breeding, Yinchuan, Ningxia Hui Aut, Peoples R China
[3] Yangzhou Univ, Coll Vet Med, Yangzhou, Jiangsu, Peoples R China
[4] Southwest Minzu Univ, Key Lab Qinghai Tibetan Plateau Anim Genet Resour, Minist Educ, Chengdu, Peoples R China
[5] Xinyang Normal Univ, Coll Life Sci, Xinyang, Peoples R China
基金
中国国家自然科学基金;
关键词
lncRNA; miRNA; circRNA; Adipose tissue; Adipogenesis; Bovine; SKELETAL-MUSCLE DEVELOPMENT; PPAR-GAMMA; ADIPOCYTE DIFFERENTIATION; ADIPOGENIC DIFFERENTIATION; FAT DEPOSITION; STEM-CELLS; PROMOTES; PROLIFERATION; SEQUENCE; GROWTH;
D O I
10.1007/s11010-021-04132-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Lipid metabolism, which encompasses synthesis and degradation of lipids, is critical for a wide range of cellular functions, including structural and morphological properties of organelles, energy storage, signalling, and the stability and function of membrane proteins. Adipose tissue is a dynamic tissue type that performs a lot of significant physiological functions, including secretion, and is involved in maintaining homeostasis and in regulatory roles of other tissues based on paracrine or endocrine. More recently, several classes of non-coding RNAs (ncRNAs), such as long non-coding RNA (lncRNA), microRNA (miRNA) and circular RNA (circRNA), have been discovered in adipocytes, and they act as critical regulators of gene expression in adipogenesis and regulate adipogenesis through multiple pathways. In the present paper, we discussed several classes of non-coding RNAs and summarized the latest research on the regulatory role of ncRNAs in bovine adipogenesis. We gave examples for known modes of action to look forward to providing reference information future scientific research in cattle breeding.
引用
收藏
页码:2837 / 2845
页数:9
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