Condensation of 1-(pyridin-4-yl)propan-2-one with 1,3,6,8-tetraazatricyclo[4.4.1.1(3,8)]dodecane gave 1-( pyridin-4-yl)-3,6-diazahomoadamantan-9-one as intermediate product in the synthesis of 1-(pyridin-4-yl)-3,6-diazahomoadamantane and its derivatives having functional substituents at the bridging carbon atom in the homoadamantane skeleton.