Riding tandem: Circadian clocks and the cell cycle

被引:174
作者
Hunt, Tim
Sassone-Corsi, Paolo
机构
[1] London Res Inst, Cell Cycle Control Lab, Clare Hall Labs, S Mimms EN6 3LD, Herts, England
[2] Univ Calif Irvine, Dept Pharmacol, Sch Med, Irvine, CA 92697 USA
关键词
D O I
10.1016/j.cell.2007.04.015
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The circadian clock, which governs metabolic and physiological rhythms in diverse organisms, shares common features with the cell cycle. Yet, these two oscillatory systems seem to be fully independent of each other. Recent studies now reveal that some essential regulatory elements are common to both the cell cycle and circadian clock.
引用
收藏
页码:461 / 464
页数:4
相关论文
共 20 条
  • [1] Requirement of mammalian Timeless for circadian rhythmicity
    Barnes, JW
    Tischkau, SA
    Barnes, JA
    Mitchell, JW
    Burgoon, PW
    Hickok, JR
    Gillette, MU
    [J]. SCIENCE, 2003, 302 (5644) : 439 - 442
  • [2] HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability
    Collis, Spencer J.
    Barber, Louise J.
    Clark, Allison J.
    Martin, Julie S.
    Ward, Jordan D.
    Boulton, Simon J.
    [J]. NATURE CELL BIOLOGY, 2007, 9 (04) : 391 - U62
  • [3] Circadian regulator CLOCK is a histone acetyltransferase
    Doi, Masao
    Hirayama, Jun
    Sassone-Corsi, Paolo
    [J]. CELL, 2006, 125 (03) : 497 - 508
  • [4] Dorée M, 2002, J CELL SCI, V115, P2461
  • [5] Molecular bases for circadian clocks
    Dunlap, JC
    [J]. CELL, 1999, 96 (02) : 271 - 290
  • [6] The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo
    Fu, LN
    Pelicano, H
    Liu, JS
    Huang, P
    Lee, CC
    [J]. CELL, 2002, 111 (01) : 41 - 50
  • [7] The circadian clock: Pacemaker and tumour suppressor
    Fu, LN
    Lee, CC
    [J]. NATURE REVIEWS CANCER, 2003, 3 (05) : 350 - 361
  • [8] The molecular clock mediates leptin-regulated bone formation
    Fu, LN
    Patel, MS
    Bradley, A
    Wagner, EF
    Karsenty, G
    [J]. CELL, 2005, 122 (05) : 803 - 815
  • [9] The circadian gene Per1 plays an important role in cell growth and DNA damage control in human cancer cells
    Gery, S
    Komatsu, N
    Baldjyan, L
    Yu, A
    Koo, D
    Koeffler, HP
    [J]. MOLECULAR CELL, 2006, 22 (03) : 375 - 382
  • [10] The F-box protein Slimb controls the levels of clock proteins Period and Timeless
    Grima, B
    Lamouroux, A
    Chélot, E
    Papin, C
    Limbourg-Bouchon, B
    Rouyer, F
    [J]. NATURE, 2002, 420 (6912) : 178 - 182