Cycloartane triterpenoid saponins from the herbs of Thalictrum fortunei

被引：5
作者：
Jiang, Si-Qi [1 ,2 ]
Zhang, Yu-Bo [1 ,2 ]
Xiao, Min [3 ,4 ]
Jiang, Lin [1 ,2 ]
Luo, Ding [1 ,2 ]
Niu, Qian-Wen [1 ,2 ]
Li, Yao-Lan [1 ,2 ]
Zhang, Xian-Tao [3 ,4 ]
Wang, Guo-Cai [1 ,2 ]
机构：
[1] Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Guangdong Prov Key Lab Pharmacodynam Constituents, Guangzhou 510632, Guangdong, Peoples R China
[3] Guangdong Inst Tradit Chinese Med, Guangzhou 510520, Guangdong, Peoples R China
[4] Guangzhou Univ Chinese Med, Guangzhou 510006, Guangdong, Peoples R China
来源：
CARBOHYDRATE RESEARCH | 2017年 / 445卷
基金：
中国国家自然科学基金;
关键词：
Thalictrum fortunei; Cycloartane triterpenoid saponins; Cytotoxicity; Antiviral activity; BENZYLISOQUINOLINE ALKALOIDS; GLYCOSIDES; CONSTITUENTS; PLANTS; MINUS;
D O I：
10.1016/j.carres.2017.03.019
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Six new cycloartane triterpenoid saponins, thalisides A-F (1-6), along with four known ones (7-10), were isolated from Thalictrum fortunei. The new structures were elucidated by using spectroscopic data (NMR, IR, UV, and MS). Compounds 1-10 were examined for their in vitro cytotoxicity against two human cancer cell lines (HepG2, A549) and antiviral activity against influenza A virus (H1N1) and found to be inactive. (C) 2017 Elsevier Ltd. All rights reserved.
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页码：1 / 6
页数：6
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