Hypertension, chronic kidney disease, and the development of cardiovascular risk: a joint primacy

被引：17

作者：

Middleton, John P. ^{[1
]}

Pun, Patrick H. ^{[1
]}

机构：

[1] Duke Univ, Dept Med, Div Nephrol, Durham, NC 27705 USA

来源：

KIDNEY INTERNATIONAL | 2010年 / 77卷 / 09期

关键词：

SUDDEN CARDIAC DEATH; LEFT-VENTRICULAR HYPERTROPHY; BLOOD-PRESSURE; OUTCOMES; PROGRESSION;

D O I：

10.1038/ki.2010.19

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with chronic kidney disease (CKD) have an inordinate risk of cardiovascular disease. In addition to the metabolic state of uremia, the CKD-associated risk is partly explainable by unique cofactors such as dyslipidemia, systemic inflammation, and exposures that occur during renal replacement therapies. However, the comorbid condition of hypertension also enhances risk in patients with CKD. New observations suggest that diminished glomerular filtration rate and hypertension share primacy in the development of cardiovascular illness. Kidney International (2010) 77, 753-755. doi: 10.1038/ki.2010.19

引用

页码：753 / 755

页数：3

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