The Development of Dendritic Gd-DTPA Complexes for MRI Contrast Agents

被引：3

作者：

Yu, Gang ^{[1
,2
,3
,4
]}

Yamashita, Mitsuji ^{[5
]}

Tian, Mei ^{[6
]}

Zhang, Hong ^{[1
,2
,3
,4
]}

Ozaki, Nobuhisa ^{[5
]}

Yamashita, Junko ^{[5
]}

Fujie, Michio ^{[7
]}

Takehar, Yasuo ^{[7
]}

Sakahara, Harumi ^{[7
]}

机构：

[1] Zhejiang Univ, Sch Med, Affiliated Hosp 2, Dept Nucl Med, Hangzhou 310009, Zhejiang, Peoples R China

[2] Zhejiang Univ, Med PET Ctr, Hangzhou 310009, Zhejiang, Peoples R China

[3] Zhejiang Univ, Inst Nucl Med & Mol Imaging, Hangzhou 310009, Zhejiang, Peoples R China

[4] Key Lab Med Mol Imaging Zhejiang Prov, Hangzhou, Zhejiang, Peoples R China

[5] Shizuoka Univ, Grad Sch Sci & Technol, Dept Nanomat, Shizuoka, Japan

[6] Univ Texas MD Anderson Canc Ctr, Dept Expt Diagnost Imaging, Houston, TX 77030 USA

[7] Hamamatsu Univ Sch Med, Dept Radiol, Shizuoka, Japan

来源：

CURRENT MEDICAL IMAGING REVIEWS | 2010年 / 6卷 / 01期

关键词：

MRI; dendritic; Gd-DTPA; contrast agents; NEUTRON-CAPTURE THERAPY; MAGNETIC-RESONANCE; DERIVATIVES; GADOLINIUM; RELAXIVITY; DYNAMICS; TUMOR; BIODISTRIBUTION; DENDRIMERS;

D O I：

10.2174/157340510790693965

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Magnetic resonance imaging (MRI) is a non-invasive and high resolution imaging technique and becomes a powerful diagnostic tool in the clinic. With the applications of MRI becoming more and more dependent on contrast agents, it is particularly important to develop efficient contrast agents. This article describes how to design an efficient dendritic Gd-DTPA complex for MRI contrast agents.

引用

页码：42 / 45

页数：4

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