Quantitative trait loci for BMD and bone strength in an intercross between domestic and wildtype chickens

被引:27
|
作者
Rubin, Carl-Johan
Brandstrom, Helena
Wright, Dominic
Kerje, Susanne
Gunnarsson, Ulrika
Schutz, Karin
Fredriksson, Robert
Jensen, Per
Andersson, Leif
Ohlsson, Claes
Mallmin, Hans
Larsson, Sune
Kindmark, Andreas [1 ]
机构
[1] Univ Uppsala Hosp, Dept Med Sci, SE-75185 Uppsala, Sweden
[2] Univ Uppsala Hosp, Dept Med Biochem & Microbiol, SE-75185 Uppsala, Sweden
[3] AgResearch, Hamilton, New Zealand
[4] Univ Uppsala Hosp, Dept Neurosci, SE-75185 Uppsala, Sweden
[5] Linkoping Univ, IFM, Linkoping, Sweden
[6] Swedish Univ Agr Sci, Dept Anim Breeding & Genet, S-75007 Uppsala, Sweden
[7] Univ Gothenburg, Sahlgrenska Hosp, Div Endocrinol, Dept Internal Med, Gothenburg, Sweden
[8] Univ Uppsala Hosp, Dept Surg Sci, Sect Orthoped, SE-75185 Uppsala, Sweden
关键词
chicken; quantitative trait loci; BMD; biomechanics;
D O I
10.1359/JBMR.061203
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
With chicken used as a model species, we used QTL analysis to examine the genetic contribution to bone traits. We report the identification of four QTLs for femoral traits: one for bone strength, one for endosteal circumference, and two affecting mineral density of noncortical bone.
引用
收藏
页码:375 / 384
页数:10
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