Is there a role of magnetic resonance imaging in deciding to stop anti-tumor necrosis factor treatment in ileal Crohn's disease?

被引：5
作者：
Gallego, Jose C. [1 ]
Echarri, Ana [2 ]
机构：
[1] Complexo Hosp Univ Ferrol, Radiol Dept, Av Residencia S-N, Ferrol 15405, Spain
[2] Complexo Hosp Univ Ferrol, Gastroenterol Dept, Ferrol, Spain
来源：
CLINICAL IMAGING | 2017年 / 43卷
关键词：
Crohn's disease; Magnetic resonance imaging; Anti-tumor necrosis factor agents; INFLAMMATORY-BOWEL-DISEASE; INFLIXIMAB THERAPY; CLINICAL REMISSION; FOLLOW-UP; DISCONTINUATION; MAINTENANCE; RELAPSE;
D O I：
10.1016/j.clinimag.2017.03.010
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Purpose: This study was performed to assess the ability of magnetic resonance enterography to predict the evolution of patients in whom anti-tumor necrosis factor-alpha therapy was suspended. Methods: A prospective study of patients with ileal Crohn's disease was performed. Results: Twenty-nine patients were included. Patients who later relapsed showed higher magnetic resonance scores than those who did not relapse (4.2 vs. 2.5, respectively; p < 0.02). The area under the receiving-operating characteristics curve was 0.755 when discriminating patients who relapsed. Conclusions: Magnetic resonance enterography should be taken into account when deciding the withdrawal of anti-tumor necrosis factor-alpha in patients with Crohn's disease. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码：175 / 179
页数：5
相关论文
共 50 条
  • [41] The Frequency of Sister Chromatid Exchanges in Patients with Crohn's Disease and the Effect of Therapy with "Anti-Tumor Necrosis Factor" on this Frequency
    Danalioglu, Ahmed
    HEPATO-GASTROENTEROLOGY, 2009, 56 (91-92) : 729 - 733
  • [42] Comparative Effectiveness and Safety of Anti-Tumor Necrosis Factor Agents in Biologic-Naive Patients With Crohn's Disease
    Singh, Siddharth
    Heien, Herbert C.
    Sangaralingham, Lindsey R.
    Schilz, Stephanie R.
    Kappelman, Michael D.
    Shah, Nilay D.
    Loftus, Edward V., Jr.
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2016, 14 (08) : 1120 - +
  • [43] Increases in Sex Hormones during Anti-Tumor Necrosis Factor a Therapy in Adolescents with Crohn's Disease
    DeBoer, Mark D.
    Thayu, Meena
    Griffin, Lindsay M.
    Baldassano, Robert N.
    Denson, Lee A.
    Zemel, Babette S.
    Denburg, Michelle R.
    Agard, Hannah E.
    Herskovitz, Rita
    Long, Jin
    Leonard, Mary B.
    JOURNAL OF PEDIATRICS, 2016, 171 : 146 - +
  • [44] Correlation Between Ultrasonographic Response and Anti-Tumor Necrosis Factor Drug Levels in Crohn's disease
    Han, Ze-Min
    Elodie, Welera Haissou
    Yan, Li-Hua
    Xu, Pei-Chun
    Zhao, Xin-Mei
    Zhi, Fa-Chao
    THERAPEUTIC DRUG MONITORING, 2022, 44 (05) : 659 - 664
  • [45] The Efficacy of Anti-Tumor Necrosis Factor Alpha for Symptomatic Stricturing Small Bowel Crohn's Disease
    Alourfi, Mansour
    Mosli, Mahmoud
    Saadah, Omar, I
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (09)
  • [46] Factors associated with anti-tumor necrosis factor effectiveness to prevent postoperative recurrence in Crohn's disease
    Buisson, Anthony
    Cannon, Lisa
    Umanskiy, Konstantin
    Hurst, Roger D.
    Hyman, Neil H.
    Sakuraba, Atsushi
    Pekow, Joel
    Dalal, Sushila
    Cohen, Russell D.
    Pereira, Bruno
    Rubin, David T.
    INTESTINAL RESEARCH, 2022, 20 (03) : 303 - +
  • [47] Defining and predicting deep remission in patients with perianal fistulizing Crohn's disease on anti-tumor necrosis factor therapy
    Konstantinos Papamichael
    Adam S Cheifetz
    World Journal of Gastroenterology, 2017, 23 (34) : 6197 - 6200
  • [48] Patient's Perspectives Important for Early Anti-Tumor Necrosis Factor Treatment in Inflammatory Bowel Disease
    Baars, Judith E.
    Siegel, Corey A.
    Kuipers, Ernst J.
    van der Woude, C. Janneke
    DIGESTION, 2009, 79 (01) : 30 - 35
  • [49] Role of magnetic resonance imaging in the management of perianal Crohn’s disease
    Jose C. Gallego
    Ana Echarri
    Insights into Imaging, 2018, 9 : 47 - 58
  • [50] Anti-Tumor Necrosis Factor-Alpha Withdrawal in Children With Inflammatory Bowel Disease in Endoscopic and Histologic Remission
    Scarallo, Luca
    Bolasco, Giulia
    Barp, Jacopo
    Bianconi, Martina
    di Paola, Monica
    Di Toma, Michele
    Naldini, Sara
    Paci, Monica
    Renzo, Sara
    Labriola, Flavio
    De Masi, Salvatore
    Alvisi, Patrizia
    Lionetti, Paolo
    INFLAMMATORY BOWEL DISEASES, 2022, 28 (02) : 183 - 191
12345