The impact of red and processed meat consumption on cancer and other health outcomes: Epidemiological evidences

被引:120
作者
Boada, Luis D. [1 ,2 ]
Henriquez-Hernandez, L. A. [1 ,2 ]
Luzardo, O. P. [1 ,2 ]
机构
[1] Univ Las Palmas Gran Canaria, Res Inst Biomed & Hlth Sci IUIBS, Toxicol Unit, Plaza Dr Pasteur S-N, Las Palmas Gran Canaria 35016, Spain
[2] Spanish Biomed Res Ctr Physiopathol Obes & Nutr C, Plaza Dr Pasteur S-N, Las Palmas Gran Canaria 35016, Spain
关键词
HETEROCYCLIC AROMATIC-AMINES; COLORECTAL-CANCER; BLADDER-CANCER; HEPATOCELLULAR-CARCINOMA; ESOPHAGEAL ADENOCARCINOMA; ORGANOCHLORINE PESTICIDES; RISK-FACTORS; HEME IRON; METAANALYSIS; DIET;
D O I
10.1016/j.fct.2016.04.008
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Meat is one of the staples of the human diet, which provides high-quality nutrients, but that also constitutes a relevant source of cholesterol and saturated fatty acids. Epidemiologic studies have linked consumption of red or processed meat with obesity, type 2 diabetes, cardiovascular diseases, and cancers. Most epidemiological studies suggest that a high intake of meat, especially processed meat, is associated with increased colorectal cancer risk. Potential reasons for the association between high meat intake and colorectal cancer risk include some chemicals naturally contained in meat, or generated by the processing and cooking. From the literature it can be concluded that there is enough epidemiological evidence linking processed meat intake and colorectal cancer risk, but there is limited evidence regarding unprocessed red meat intake and the disease. On the contrary, there is only limited evidence linking meat intake with other diseases such as cardiovascular disease, type 2 diabetes or other cancers. Nevertheless, the literature suggest that dietary intervention may be a promising approach for prevention of cancers of the colon, esophagus, liver, stomach and bladder, and type 2 diabetes and cardiovascular disease which still need to be confirmed by further well designed prospective studies and experimental research. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码:236 / 244
页数:9
相关论文
共 104 条
[1]   Association between total, processed, red and white meat consumption and all-cause, CVD and IHD mortality: a meta-analysis of cohort studies [J].
Abete, Itziar ;
Romaguera, Dora ;
Vieira, Ana Rita ;
Lopez de Munain, Adolfo ;
Norat, Teresa .
BRITISH JOURNAL OF NUTRITION, 2014, 112 (05) :762-775
[2]   Meat, dairy, and cancer [J].
Abid, Zaynah ;
Cross, Amanda J. ;
Sinha, Rashmi .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2014, 100 (01) :386S-393S
[3]   Exposure to heterocyclic aromatic amines from the consumption of cooked red meat and its effect on human cancer risk: A review [J].
Alaejos, M. S. ;
Gonzalez, V. ;
Afonso, A. M. .
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2008, 25 (01) :2-24
[4]   Polymorphisms of glutathione S-transferase μ and θ, MDR1 and VEGF genes as risk factors of bladder cancer: A case-control study [J].
Alberto Henriquez-Hernandez, Luis ;
Navarro, Patricio ;
Luzardo, Octavio P. ;
Elisa Alvarez-Leon, Eva ;
Boada, Luis D. ;
Zumbado, Manuel ;
Pestano, Jose ;
Suarez, Javier R. ;
Chesa, Nicolas ;
Almeida, Maira ;
Valeron, Pilar F. .
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2012, 30 (05) :660-665
[5]   A review and meta-analysis of prospective studies of red and processed meat intake and prostate cancer [J].
Alexander, Dominik D. ;
Mink, Pamela J. ;
Cushing, Colleen A. ;
Sceurman, Bonnie .
NUTRITION JOURNAL, 2010, 9
[6]  
[Anonymous], CRIT REV FOOD SCI NU
[7]  
[Anonymous], 2011, COL CANC 2011 REP FO
[8]  
[Anonymous], 2007, FOOD NUTR PHYS ACT P
[9]  
[Anonymous], 1978, IARC MON EV CARC RIS
[10]  
[Anonymous], P NUTR SOC