The effects of artificial selection on genetic variation of some immune genes in Gallus gallus

To research effects of the artificial selection of Gallus gallus on G. domesticus' nucleotide diversity of immune genes, sequence polymorphisms of G. domesticus (23 genes), G. gallus (23 genes), G. lafayetti (17 genes), and G. sonneratii (17 genes) were obtained from GenBank. The data set included 819 polymorphisms. Immune gene polymorphism and selection efficiency in the data from those four species of Gallus were calculated. By calculating the q(w) (Watterson's estimator) of each site, an average q(w) for each species and the minimum number of re-combinations in each species and by estimating the selection efficiency for G. domesticus and G. gallus, neither significant nucleotide diversity nor genetic-diversity-q(w) difference was found between G. domesticus and G. gallus. The results indicated that the patterns of genetic diversity in G. domesticus were strongly influenced by recombination and, because Tajima's D has a negative value, recombination was the main mechanism responsible for the immune gene evolution of G. gallus.