A case of canine central nervous system cryptococcosis: Management with fluconazole

被引：36
作者：
Tiches, D [1 ]
Vite, CH
Dayrell-Hart, B
Steinberg, SA
Gross, S
Lexa, F
机构：
[1] Univ Penn, Sch Vet Med, Dept Clin Studies, Philadelphia, PA 19104 USA
[2] Univ Penn, Sch Med, Philadelphia, PA 19104 USA
来源：
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION | 1998年 / 34卷 / 02期
关键词：
D O I：
10.5326/15473317-34-2-145
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
A three-year-old, female Labrador retriever was presented for acute generalized seizures. Disseminated cryptococcosis with central nervous system (CNS) involvement was diagnosed by serum and cerebrospinal fluid (CSF) fungal titers, histopathological examination, and magnetic resonance imaging (MRI). Fluconazole therapy resulted in prolonged, substantial clinical improvement for a period of one year. This report documents the diagnosis of a case of cryptococcal meningoencephalitis and its management with the new antifungal agent, fluconazole.
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页码：145 / 151
页数：7
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