Which clinical studies provide the best evidence? The best RCT still trumps the best observational study

被引:255
作者
Barton, S [1 ]
机构
[1] BMA House, London WC1H 9JR, England
关键词
D O I
10.1136/bmj.321.7256.255
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
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页码:255 / 256
页数:2
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共 11 条
[1]  
[Anonymous], 1994, RETHINKING EVIDENCE
[2]  
[Anonymous], HLTH TECHNOL ASSESS
[3]   A comparison of observational studies and randomized, controlled trials. [J].
Benson, K ;
Hartz, AJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (25) :1878-1886
[4]   EVIDENCE FAVORING USE OF ANTICOAGULANTS IN HOSPITAL PHASE OF ACUTE MYOCARDIAL-INFARCTION [J].
CHALMERS, TC ;
MATTA, RJ ;
SMITH, H ;
KUNZLER, AM .
NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (20) :1091-1096
[5]   Randomized, controlled trials, observational studies, and the hierarchy of research designs. [J].
Concato, J ;
Shah, N ;
Horwitz, RI .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (25) :1887-1892
[6]   Is screening for breast cancer with mammography justifiable? [J].
Gotzsche, PC ;
Olsen, O .
LANCET, 2000, 355 (9198) :129-134
[7]   Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women [J].
Hulley, S ;
Grady, D ;
Bush, T ;
Furberg, C ;
Herrington, D ;
Riggs, B ;
Vittinghoff, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (07) :605-613
[8]   The unpredictability paradox: review of empirical comparisons of randomised and non-randomised clinical trials [J].
Kunz, R ;
Oxman, AD .
BRITISH MEDICAL JOURNAL, 1998, 317 (7167) :1185-1190
[9]   Randomized trials or observational tribulations? [J].
Pocock, SJ ;
Elbourne, DR .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (25) :1907-1909
[10]   Evidence based medicine: What it is and what it isn't - It's about integrating individual clinical expertise and the best external evidence [J].
Sackett, DL ;
Rosenberg, WMC ;
Gray, JAM ;
Haynes, RB ;
Richardson, WS .
BRITISH MEDICAL JOURNAL, 1996, 312 (7023) :71-72