Enantiomeric separation of d-/l-norepinephrine and -epinephrine by high-performance liquid chromatography with a β-cyclodextrin type chiral stationary phase

被引：1
|
作者：
Fukushima, T [1 ]
Murayama, K [1 ]
Santa, T [1 ]
Homma, H [1 ]
Imai, K [1 ]
机构：
[1] Univ Tokyo, Fac Pharmaceut Sci, Bunkyo Ku, Tokyo 113, Japan
来源：
BIOMEDICAL CHROMATOGRAPHY | 1998年 / 12卷 / 01期
关键词：
beta-cyclodextrin chiral stationary phase; epinephrine; norepinephrine; enantiomer; HPLC;
D O I：
10.1002/(SICI)1099-0801(199801/02)12:1<1::AID-BMC694>3.0.CO;2-W
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Enantiomeric separation of d-/l-norepinephrine (NE) and d-/l-epinephrine (E) was investigated with various mobile phases by high-performance liquid chromatography using a beta-cyclodextrin type chiral stationary phase as a chiral column, The mobile phase of 2.5 M phosphate buffer (pH 3.0) gave separation factors (alpha s) of 1.04 and 1.06 for NE and E, respectively. (C) 1998 John Wiley & Sons, Ltd.
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页码：1 / 3
页数：3
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