Polymer-Based Electrospun Nanofibers for Biomedical Applications

被引：163

作者：

Al-Enizi, Abdullah M. ^{[1
]}

Zagho, Moustafa M. ^{[2
]}

Elzatahry, Ahmed A. ^{[2
]}

机构：

[1] King Saud Univ, Dept Chem, POB 2455, Riyadh 11451, Saudi Arabia

[2] Qatar Univ, Coll Arts & Sci, Mat Sci & Technol Program, POB 2713, Doha, Qatar

来源：

NANOMATERIALS | 2018年 / 8卷 / 04期

关键词：

electrospinning; nanofibers; medical prostheses; wound dressing; drug release; tissue engineering; blood vessels; bone; CONTROLLED DRUG-RELEASE; COMPOSITE NANOFIBERS; ANTIBACTERIAL PROPERTIES; VASCULAR GRAFTS; TETRACYCLINE HYDROCHLORIDE; QUATERNIZED CHITOSAN; EXTRACELLULAR-MATRIX; DRESSING MATERIALS; TUBULAR SCAFFOLD; IN-VITRO;

D O I：

10.3390/nano8040259

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrospinning has been considered a promising and novel procedure to fabricate polymer nanofibers due to its simplicity, cost effectiveness, and high production rate, making this technique highly relevant for both industry and academia. It is used to fabricate non-woven fibers with unique characteristics such as high permeability, stability, porosity, surface area to volume ratio, ease of functionalization, and excellent mechanical performance. Nanofibers can be synthesized and tailored to suit a wide range of applications including energy, biotechnology, healthcare, and environmental engineering. A comprehensive outlook on the recent developments, and the influence of electrospinning on biomedical uses such as wound dressing, drug release, and tissue engineering, has been presented. Concerns regarding the procedural restrictions and research contests are addressed, in addition to providing insights about the future of this fabrication technique in the biomedical field.

引用

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